44 results found
  1. November 2015

    Episode 25: November 2015

    In this episode we hear about deep-sea bacteria, cigarette smoke and lung disease, antibiotic resistance, unconscious perception, and the benefits of sleep.
  2. December 2013

    Episode 7: December 2013

    In this episode we hear about drug resistance, severe brain damage, sugar versus sweetener, public goods dilemmas, and the evolution of the machinary that makes proteins in cells.
    1. Neuroscience

    Increasing suppression of saccade-related transients along the human visual hierarchy

    Tal Golan et al.
    Similar to spontaneous eye blinks perceptual stability, despite small saccades, is related to actively silencing transients in the high-level ends of both ventral and dorsal visual cortices, while activity in low-level visual cortex remains unstable.
    1. Human Biology and Medicine
    2. Neuroscience

    Localization of spontaneous bursting neuronal activity in the preterm human brain with simultaneous EEG-fMRI

    Tomoki Arichi et al.
    Direct measure of neural and hemodynamic activity in the developing human brain shows that the insula is a major source of transient bursting events that are critical for cortical maturation.
    1. Neuroscience

    Human intracranial recordings link suppressed transients rather than 'filling-in' to perceptual continuity across blinks

    Tal Golan et al.
    The brain ensures that blinks do not disrupt vision by deleting signals that represent discontinuities in visual input, rather than by recreating the missing input.
    1. Neuroscience

    Irregular spiking of pyramidal neurons organizes as scale-invariant neuronal avalanches in the awake state

    Timothy Bellay et al.
    Spontaneous, irregular spiking in single cortical pyramidal neurons assembles as neuronal avalanches at the group level identifying a robust scale-invariant organization of resting activity in the awake state.
    1. Neuroscience

    Parvalbumin-positive interneurons mediate neocortical-hippocampal interactions that are necessary for memory consolidation

    Frances Xia et al.
    Electrophysiological and behavioural experiments reveal that parvalbumin interneuron-mediated increases in neocortical-hippocampal interactions are necessary for successful memory consolidation.
    1. Human Biology and Medicine
    2. Neuroscience

    Early tissue damage and microstructural reorganization predict disease severity in experimental epilepsy

    Philipp Janz et al.
    Non-invasive imaging of hippocampal neurodegeneration and structural reorganization during epileptogenesis allows the prediction of disease severity in mesial temporal lobe epilepsy, which may facilitate the early pharmacological intervention before seizure onset.
    1. Human Biology and Medicine
    2. Immunology and Inflammation

    Female resistance to pneumonia identifies lung macrophage nitric oxide synthase-3 as a therapeutic target

    Zhiping Yang et al.
    Activation of lung macrophage nitric oxide synthase-3 improves both bacterial clearance and outcome in primary and secondary pneumonia models.
    1. Human Biology and Medicine
    2. Neuroscience

    Point of View: Predictive regulation and human design

    Peter Sterling
    Why does the human regulatory system, which evolution tuned for small satisfactions, now constantly demand 'more'?

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