1,651 results found
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    DNA-PK is a DNA sensor for IRF-3-dependent innate immunity

    Brian J Ferguson, Daniel S Mansur ... Geoffrey L Smith
    Experiments in mice have shown than an enzyme that repairs broken DNA inside the nucleus also has a central role in the innate immune system because it is able to detect foreign DNA outside the nucleus.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    A novel GTP-binding protein–adaptor protein complex responsible for export of Vangl2 from the trans Golgi network

    Yusong Guo, Giulia Zanetti, Randy Schekman
    The ability of epithelial cells to distinguish between domains on opposing cell surfaces within a tissue, a property known as planar cell polarity, relies on proteins and protein complexes directing the traffic of signaling proteins to specific locations on the cell surface membrane.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Influenza-virus membrane fusion by cooperative fold-back of stochastically induced hemagglutinin intermediates

    Tijana Ivanovic, Jason L Choi ... Stephen C Harrison
    Long-lived intermediate states formed by glycoprotein catalysts are an essential part of the process used by influenza virus particles to infect cells.
    1. Neuroscience

    Kinesin-1 regulates dendrite microtubule polarity in Caenorhabditis elegans

    Jing Yan, Dan L Chao ... Kang Shen
    A cellular motor protein helps to ensure that microtubules are oriented correctly within neuronal dendrites
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K+ channel

    Anirban Banerjee, Alice Lee ... Roderick MacKinnon
    Charybdotoxin, a toxin produced by scorpions, blocks a K+ channel by binding in a lock-and-key fashion to the mouth of the channel and presenting a lysine amino group, which serves as a K+ mimic in the selectivity filter.
    1. Plant Biology

    Temporal transcriptional response to ethylene gas drives growth hormone cross-regulation in Arabidopsis

    Katherine Noelani Chang, Shan Zhong ... Joseph R Ecker
    The plant hormone ethylene regulates the expression of multiple genes in the model plant Arabidopsis, including those that respond to other hormones.
    1. Stem Cells and Regenerative Medicine
    2. Microbiology and Infectious Disease

    Functional genomic characterization of neoblast-like stem cells in larval Schistosoma mansoni

    Bo Wang, James J Collins III, Phillip A Newmark
    Cells that give rise to the infectious form of parasitic flatworms called schistosomes show similar patterns of gene expression to stem cells in free-living flatworms.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Minor introns are embedded molecular switches regulated by highly unstable U6atac snRNA

    Ihab Younis, Kimberly Dittmar ... Gideon Dreyfuss
    Hundreds of cell growth and stress response genes are controlled by a rare small RNA component of an ancient splicing machinery, providing a raison d'être for its previously unexplained evolutionary conservation.
    1. Developmental Biology

    Cellular resolution models for even skipped regulation in the entire Drosophila embryo

    Garth R Ilsley, Jasmin Fisher ... Nicholas M Luscombe
    A statistical model is able to predict patterns of gene expression output in Drosophila embryos using only the cellular concentrations of transcription factors as input.
    1. Stem Cells and Regenerative Medicine

    Mammalian genes induce partially reprogrammed pluripotent stem cells in non-mammalian vertebrate and invertebrate species

    Ricardo Antonio Rosselló, Chun-Chun Chen ... Erich D Jarvis
    Cells from vertebrate and invertebrate model systems can be reprogrammed into stem-like cells using mouse genes.

Refine your results by:

Type
Research categories