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Page 3 of 166
    1. Ecology

    Linking spatial patterns of terrestrial herbivore community structure to trophic interactions

    Jakub Witold Bubnicki, Marcin Churski ... Dries PJ Kuijper
    The spatial interactions between humans, large carnivores and herbivores cascade down in a complex but predictable way to lower trophic levels affecting regeneration of tree species in a temperate forest.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Dpp dependent Hematopoietic stem cells give rise to Hh dependent blood progenitors in larval lymph gland of Drosophila

    Nidhi Sharma Dey, Parvathy Ramesh ... Lolitika Mandal
    Identification of Hematopoietic stem cells (HSCs) in the genetically amenable organism Drosophila melanogaster paves the path to address HSC biology, both in normal and pathophysiological conditions.
    1. Biochemistry and Chemical Biology

    Structural and functional characterization of G protein–coupled receptors with deep mutational scanning

    Eric M Jones, Nathan B Lubock ... Sriram Kosuri
    Linking deep mutational scanning with engineered transcriptional reporters in human cell lines establishes a generalizable method for exploring pharmacogenomics, structure, and function across broad classes of drug receptors.
    1. Ecology
    2. Genetics and Genomics

    Non-invasive real-time genomic monitoring of the critically endangered kākāpō

    Lara Urban, Allison K Miller ... Andrew Digby
    The application of real-time genomics by long-read nanopore sequencing to environmental samples creates a new trajectory for non-invasive genomics-based monitoring of critically endangered wildlife.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    The guide sRNA sequence determines the activity level of box C/D RNPs

    Andrea Graziadei, Frank Gabel ... Teresa Carlomagno
    Integrative structural biology reveals a conformational equilibrium in the Box C/D methylation enzyme that regulates the extent of site-specific 2'-O-rRNA methylation in dependence of the RNA sequence.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Structure of the germline genome of Tetrahymena thermophila and relationship to the massively rearranged somatic genome

    Eileen P Hamilton, Aurélie Kapusta ... Robert S Coyne
    The model organism Tetrahymena thermopile carries two nuclei with distinct genomes: an unrearranged germline genome with five chromosomes, and a somatic genome reduced in size by a third and with 181 chromosomes.
    1. Plant Biology

    Landscape genomic prediction for restoration of a Eucalyptus foundation species under climate change

    Megan Ann Supple, Jason G Bragg ... Justin O Borevitz
    Empirical patterns of genomic and phenotypic variation across the landscape are used to develop a predictive model that will help build resilient ecological communities.
    1. Ecology
    2. Epidemiology and Global Health

    Point of View: The biospheric emergency calls for scientists to change tactics

    Fernando Racimo, Elia Valentini ... Julia B Halder
    The ever-worsening climate and ecological crises calls for life scientists to engage in advocacy and activism to galvanise governments and the public into action.
    1. Evolutionary Biology
    2. Genetics and Genomics

    GENESPACE tracks regions of interest and gene copy number variation across multiple genomes

    John T Lovell, Avinash Sreedasyam ... Jeremy Schmutz
    GENESPACE lets users track related chromosomal sequences across multiple reference genomes.
    1. Ecology

    Genomic adaptations in information processing underpin trophic strategy in a whole-ecosystem nutrient enrichment experiment

    Jordan G Okie, Amisha T Poret-Peterson ... James J Elser
    Trait-based metagenomic analysis of an ecosystem fertilization experiment shows that genomic traits that affect the costs and rates of biochemical information-processing mediate community assembly.