Spatially coordinated apical constriction occurs during Drosophila salivary gland invagination, but the salivary gland can form fully internalized and elongated tubes even when this process is completely blocked.
High-resolution live imaging analysis shows a constriction mechanism that drives zebrafish optic cup morphogenesis and highlights the role of the extracellular matrix in transmitting tensions beyond the cellular level.
Positive feedback between contractile ring myosin and compression-driven cortical flow can explain the exponential accumulation of contractile ring components and constriction rate acceleration that ensures timely cell separation during cytokinesis.
A new approach using combination of electron microscopy (EM) and high-speed atomic force microscopy (HS-AFM) clearly demonstrates dynamics of dynamin-amphiphysin complexes during membrane constriction and fission suggesting a novel 'clusterase' model of the dynamin-mediated membrane fission.
Condensation and segregation of chromosomes during mitosis is caused by a combination of short-range interactions between nucleosomes and the long-range contraction of chromosome arms mediated by condensin.
The protein CpoB regulates PBP1B activity in response to the Tol energy state, which facilitates feedback and synchronicity between envelope constriction processes during Gram-negative bacterial cell division.
A mutation that causes heart disease in humans increases the number of active myosin heads during contraction in the muscles of fruit flies, leading to the progressive dysfunction of the flight muscles and heart tube.