4,622 results found
    1. Neuroscience

    DeepEthogram, a machine learning pipeline for supervised behavior classification from raw pixels

    James P Bohnslav, Nivanthika K Wimalasena ... Christopher D Harvey
    DeepEthogram automatically classifies animal behavior videos into researcher-defined behaviors of interest, saving researcher time and enabling more detailed downstream analysis of behavior.
    1. Neuroscience

    Neural precursors of decisions that matter—an ERP study of deliberate and arbitrary choice

    Uri Maoz, Gideon Yaffe ... Liad Mudrik
    The readiness potential—a long-established neural precursor of voluntary action claimed to precede the onset of the conscious decision to move—is absent, or at least significantly reduced, for deliberate decisions.
    1. Developmental Biology

    Basement membranes are crucial for proper olfactory placode shape, position and boundary with the brain, and for olfactory axon development

    Pénélope Tignard, Karen Pottin ... Marie Anne Breau
    Laminin gamma1-dependent basement membranes are required for multiple aspects of olfactory system development in zebrafish, including the maintenance of placode tissue shape and the growth of the olfactory axons.
    1. Physics of Living Systems
    2. Cell Biology

    Mechanical heterogeneity along single cell-cell junctions is driven by lateral clustering of cadherins during vertebrate axis elongation

    Robert J Huebner, Abdul Naseer Malmi-Kakkada ... John B Wallingford
    Very local molecular patterns impart precise changes in the local mechanics of individual cell-cell junctions.
    1. Chromosomes and Gene Expression

    Evidence that Mediator is essential for Pol II transcription, but is not a required component of the preinitiation complex in vivo

    Natalia Petrenko, Yi Jin ... Kevin Struhl
    Mediator, a transcriptional coactivator complex, is essential for transcription but is not a required component of a functional preinitiation complex, indicating that Mediator is not equivalent to a general transcription factor.
    1. Neuroscience

    Space as a scaffold for rotational generalisation of abstract concepts

    Jacques Pesnot Lerousseau, Christopher Summerfield
    Spatial mapping serves as a cognitive scaffold for acquiring abstract conceptual invariances across sensory domains, shedding light on the mechanisms of human learning.
    1. Physics of Living Systems

    Active morphogenesis of patterned epithelial shells

    Diana Khoromskaia, Guillaume Salbreux
    An epithelium modelled as an active, nematic surface can display flattening, budding, and tubulation morphogenetic events, which are observed during development in biological organisms.
    1. Neuroscience

    A theory of joint attractor dynamics in the hippocampus and the entorhinal cortex accounts for artificial remapping and grid cell field-to-field variability

    Haggai Agmon, Yoram Burak
    A theory of coordinated neural network dynamics in multiple brain areas offers an explanation for several recent experimental findings in the hippocampus and medial entorhinal cortex.
    1. Cancer Biology
    2. Cell Biology

    Human pancreatic cancer cell exosomes, but not human normal cell exosomes, act as an initiator in cell transformation

    Karoliina Stefanius, Kelly Servage ... Kim Orth
    Exosomes secreted from pancreatic cancer cells can function as a classic initiator in the multi-step cellular transformation process.
    1. Evolutionary Biology

    The Jurassic rise of squamates as supported by lepidosaur disparity and evolutionary rates

    Arnau Bolet, Thomas L Stubbs ... Michael J Benton
    Evidence for a largely unexplored radiation of squamates (lizards, snakes, and amphisbaenians) in the Middle to Late Jurassic is revealed by analyses of morphospace expansion, disparity, and evolutionary rates.

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