18,192 results found
    1. Neuroscience

    Data-driven reduction of dendritic morphologies with preserved dendro-somatic responses

    Willem AM Wybo, Jakob Jordan ... Walter Senn
    A flexible and accurate methodology to fit reduced compartmental models to dendritic morphologies shows that models with very few compartments can capture many dendritic computations.
    1. Computational and Systems Biology

    Network design principle for robust oscillatory behaviors with respect to biological noise

    Lingxia Qiao, Zhi-Bo Zhang ... Lei Zhang
    Searching all two- and three-node gene regulatory network topologies identifies the repressilator with positive autoregulation as the motif capable of accurate oscillation and reveals the long period and high amplitude as two distinct mechanisms for buffering different noise.
    1. Neuroscience

    A parameter-free statistical test for neuronal responsiveness

    Jorrit S Montijn, Koen Seignette ... J Alexander Heimel
    A simple and robust statistical test for neuronal stimulus response, that outperforms PSTH-based approaches such as t-tests and ANOVAs.
    1. Neuroscience

    Resonating neurons stabilize heterogeneous grid-cell networks

    Divyansh Mittal, Rishikesh Narayanan
    Intrinsic neuronal resonance stabilizes heterogeneous neural networks by suppressing low-frequency perturbations.
    1. Physics of Living Systems

    Toward Stable Replication of Genomic Information in Pools of RNA Molecules

    Ludwig Burger, Ulrich Gerland
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Developmental Biology
    2. Genetics and Genomics

    Quantitative trait and transcriptome analysis of genetic complexity underpinning cardiac interatrial septation in mice using an advanced intercross line

    Mahdi Moradi Marjaneh, Edwin P Kirk ... Richard P Harvey
    A high-resolution picture of genetic complexity and network perturbations underlying cardiac inter-atrial septal dysmorphology associated with patent foramen ovale, a common human congenital anomaly, using quantitative trait locus mapping, genome sequencing, and transcriptomics in a mouse model.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Recurrent evolution of high virulence in isolated populations of a DNA virus

    Tom Hill, Robert L Unckless
    The same host–virus interactions can evolve multiple times in nature, due to the high effective mutation rate of viruses, and provide interesting systems of study.
    1. Neuroscience
    2. Computational and Systems Biology

    A common alteration in effort-based decision-making in apathy, anhedonia, and late circadian rhythm

    Sara Z. Mehrhof, Camilla L. Nord
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Trends in Self-citation Rates in High-impact Neurology, Neuroscience, and Psychiatry Journals

    Matthew Rosenblatt, Saloni Mehta ... Dustin Scheinost
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Microbiology and Infectious Disease

    Wag31, a membrane tether, is crucial for lipid homeostasis in mycobacteria

    Yogita Kapoor, Himani Khurana ... Vinay Kumar Nandicoori
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete

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