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    1. Neuroscience

    S-cone photoreceptors in the primate retina are functionally distinct from L and M cones

    Jacob Baudin, Juan M Angueyra ... Fred Rieke
    Heterogeneity in perceptual sensitivity of human cone-mediated vision across wavelength originates in the cone photoreceptors, where S cones exhibit distinct functional properties in comparison to L and M cones.
    1. Neuroscience

    Cortical magnification eliminates differences in contrast sensitivity across but not around the visual field

    Michael Jigo, Daniel Tavdy ... Marisa Carrasco
    Scaling stimulus size based on the extent of its representation in visual cortex eliminates differences in contrast sensitivity and acuity when measured as a function of eccentricity, but not when measured as a function of polar angle.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Context-enriched interactome powered by proteomics helps the identification of novel regulators of macrophage activation

    Arda Halu, Jian-Guo Wang ... Amitabh Sharma
    Enriching the interactome with context-specific information from proteomics helps the identification of novel regulators of macrophage activation.
    1. Neuroscience

    Dynamic encoding of social threat and spatial context in the hypothalamus

    Piotr Krzywkowski, Beatrice Penna, Cornelius T Gross
    Threat and context-responsive neurons in the ventromedial hypothalamus are reshaped by experience to drive social avoidance.
    1. Microbiology and Infectious Disease

    A Tad-like apparatus is required for contact-dependent prey killing in predatory social bacteria

    Sofiene Seef, Julien Herrou ... Tâm Mignot
    First identification of the molecular determinants driving contact-dependent predation in Myxococcus..
    1. Neuroscience

    Hunger- and thirst-sensing neurons modulate a neuroendocrine network to coordinate sugar and water ingestion

    Amanda J González Segarra, Gina Pontes ... Kristin Scott
    A peptidergic network translates internal nutrient abundance cues into the coordinated regulation of sugar and water ingestion.
    1. Cancer Biology
    2. Computational and Systems Biology

    High-content microscopy reveals a morphological signature of bortezomib resistance

    Megan E Kelley, Adi Y Berman ... Gregory P Way
    Morphological profiling of untreated HCT116 cells using Cell Painting reveals a signature of bortezomib resistance, providing a proof-of-concept for the unbiased analysis of drug resistance.
    1. Genetics and Genomics
    2. Neuroscience

    Epigenomic landscapes of retinal rods and cones

    Alisa Mo, Chongyuan Luo ... Jeremy Nathans
    Genome-wide analysis of DNA methylation and accessible chromatin shows that retinal rods and cones have distinct epigenomic features that reflect differences in their development and function.
    1. Neuroscience

    Cortical network architecture for context processing in primate brain

    Zenas C Chao, Yasuo Nagasaka, Naotaka Fujii
    Large-scale electrocorticography and big data analysis of brain-wide neuronal interactions reveal the architecture of network information flow for context processing in primate brain.
    1. Computational and Systems Biology

    Antibiotic-induced population fluctuations and stochastic clearance of bacteria

    Jessica Coates, Bo Ryoung Park ... Minsu Kim
    The extinction of bacterial populations by antibiotics is stochastic and can be predicted only probabilistically, not deterministically.