398 results found
    1. Computational and Systems Biology
    2. Developmental Biology

    An image-based data-driven analysis of cellular architecture in a developing tissue

    Jonas Hartmann, Mie Wong ... Darren Gilmour
    A computational strategy for extracting representative numerical features from 3D microscopy data enables in-depth quantitative analysis of cell and tissue organization through machine learning-driven data integration and context-guided visualization.
    1. Cancer Biology
    2. Cell Biology

    Science Forum: Nanoscape, a data-driven 3D real-time interactive virtual cell environment

    Shereen R Kadir, Andrew Lilja ... John McGhee
    Computer visualization techniques developed for video games can be repurposed to enable viewers to explore cells and their environment in three dimensions.
    1. Neuroscience
    2. Physics of Living Systems

    Nested mechanosensory feedback actively damps visually guided head movements in Drosophila

    Benjamin Cellini, Jean-Michel Mongeau
    Motor context and mechanosensory feedback together influence how flies control head movements during visually guided flight maneuvers.
    1. Neuroscience

    Non-linear dimensionality reduction on extracellular waveforms reveals cell type diversity in premotor cortex

    Eric Kenji Lee, Hymavathy Balasubramanian ... Chandramouli Chandrasekaran
    WaveMAP is a novel approach that combines nonlinear dimensionality reduction with graph clustering on extracellular waveforms to reveal previously obscured cell type diversity in monkey cortex.
    1. Cell Biology

    Science Forum: Vision, challenges and opportunities for a Plant Cell Atlas

    Plant Cell Atlas Consortium, Suryatapa Ghosh Jha ... Seung Y Rhee
    A Plant Cell Atlas that shows the location and organization of molecules at cellular and tissue levels could have far-reaching consequences for plant sciences.
    1. Neuroscience

    5-HT2a receptor in mPFC influences context-guided reconsolidation of object memory in perirhinal cortex

    Juan Facundo Morici, Magdalena Miranda ... Noelia V Weisstaub
    Serotonin, a neurotransmitter mostly studied in relation with emotions, also plays an important role in the control of episodic memories.
    1. Computational and Systems Biology
    2. Medicine

    An integrative model of cardiometabolic traits identifies two types of metabolic syndrome

    Amit Frishberg, Inge van den Munckhof ... Irit Gat-Viks
    A novel type of metabolic syndrome, derived from computational modeling of phenotypic diversity in normal physiological settings, increases the risk of certain complex diseases.
    1. Neuroscience

    Differential functions of the dorsal and intermediate regions of the hippocampus for optimal goal-directed navigation in VR space

    Hyeri Hwang, Seung-Woo Jin, Inah Lee
    The intermediate region of the hippocampus is critical for strategic goal-directed navigation to the higher-value location, whereas the dorsal hippocampus implements the precise targeting of the goal location.
    1. Structural Biology and Molecular Biophysics

    Streamlining segmentation of cryo-electron tomography datasets with Ais

    Mart GF Last, Leoni Abendstein ... Thomas H Sharp
    The software package Ais simplifies automated segmentation in cryo-electron tomography, enabling users to segment, detect particles, and visualize data in a streamlined and accessible workflow.
    1. Genetics and Genomics
    2. Structural Biology and Molecular Biophysics

    Structure-guided isoform identification for the human transcriptome

    Markus J Sommer, Sooyoung Cha ... Steven L Salzberg
    The ability to accurately predict a protein's structure gives us an entirely new way to annotate the human genome.

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