5,562 results found
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    Codon choice directs constitutive mRNA levels in trypanosomes

    Janaina de Freitas Nascimento, Steven Kelly ... Mark Carrington
    The information for mRNAs expression level is set by codon choice in trypanosomes and requires translation to be interpreted into a turnover rate.
    1. Cell Biology
    2. Developmental Biology

    Continuous muscle, glial, epithelial, neuronal, and hemocyte cell lines for Drosophila research

    Nikki Coleman-Gosser, Yanhui Hu ... Amanda Simcox
    Lineage-specific Drosophila cell lines provide in vitro models for cell, biochemical, and high-throughput analyses in defined cell types.
    1. Computational and Systems Biology

    Environmental fluctuations reshape an unexpected diversity-disturbance relationship in a microbial community

    Christopher P Mancuso, Hyunseok Lee ... Ahmad S Khalil
    Laboratory experiments using a microbial community and mathematical modeling reveal how environmental disturbances can predictably alter the diversity and composition of an ecosystem.
    1. Evolutionary Biology

    Behavioural diversity of bonobo prey preference as a potential cultural trait

    Liran Samuni, Franziska Wegdell, Martin Surbeck
    Bonobo groups that share overlapping ranging areas and engage in regular social exchange show "behavioural group identity" of hunting techniques in the absence of local ecological variation.
    1. Stem Cells and Regenerative Medicine

    Complete suspension culture of human induced pluripotent stem cells supplemented with suppressors of spontaneous differentiation

    Mami Matsuo-Takasaki, Sho Kambayashi ... Yohei Hayashi
    Adding suppressors of spontaneous differentiation enables precise control of human induced pluripotent stem cell (hiPSC) status in suspension culture conditions and leads to scalable and automated cell therapy using hiPSCs.
    1. Computational and Systems Biology
    2. Neuroscience

    Early lock-in of structured and specialised information flows during neural development

    David P Shorten, Viola Priesemann ... Joseph T Lizier
    In developing neural cell cultures, information flows lock-in early and nodes undertake specialised computational roles.
    1. Neuroscience

    Tonic firing mode of midbrain dopamine neurons continuously tracks reward values changing moment-by-moment

    Yawei Wang, Osamu Toyoshima ... Masayuki Matsumoto
    Although the phasic activity of midbrain dopamine neurons is known to represent reward values, these neurons displayed a tonic firing mode to continuously track reward values changing moment-by-moment.
    1. Cell Biology
    2. Neuroscience

    Visualizing cellular and tissue ultrastructure using Ten-fold Robust Expansion Microscopy (TREx)

    Hugo GJ Damstra, Boaz Mohar ... Paul W Tillberg
    Ten-fold Robust Expansion Microscopy (TREx) is a new method for 10-fold physical expansion of specimens in one round of gel embedding, enabling nanoscale imaging of antibody stains and ultrastructural detail.
    1. Neuroscience

    RatInABox, a toolkit for modelling locomotion and neuronal activity in continuous environments

    Tom M George, Mehul Rastogi ... Caswell Barry
    A new python package standardises and simplifies how spatial behaviour and neural representations are modelled in continuous environments.
    1. Neuroscience

    Temporally delayed linear modelling (TDLM) measures replay in both animals and humans

    Yunzhe Liu, Raymond J Dolan ... Timothy E Behrens
    Temporally delayed linear modelling provides a domain-general linear framework for sequence detection and statistical testing, and is able to detect replays in both human neuroimaging and animal electrophysiology.

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