185 results found
    1. Neuroscience

    A new ‘CFS tracking’ paradigm reveals uniform suppression depth regardless of target complexity or salience

    David Alais, Jacob Coorey ... Matthew J Davidson
    A new and efficient continuous flash suppression (CFS) method is presented that provides breakthrough and suppression thresholds to quantify depth of target suppression.
    1. Neuroscience

    Emotional faces guide the eyes in the absence of awareness

    Petra Vetter, Stephanie Badde ... Marisa Carrasco
    When emotional faces are rendered invisible, our eyes look towards fearful faces and away from angry faces.
    1. Neuroscience

    Bottom-up and top-down influences at untrained conditions determine perceptual learning specificity and transfer

    Ying-Zi Xiong, Jun-Yun Zhang, Cong Yu
    Perceptual learning is specific because of the absence of bottom-up stimulation and top-down modulation at the untrained conditions.
    1. Neuroscience

    A simple retinal mechanism contributes to perceptual interactions between rod- and cone-mediated responses in primates

    William N Grimes, Logan R Graves ... Fred Rieke
    A combination of physiological and perceptual experiments show that the responses of rod photoreceptors inhibit those of cones more than vice versa, and reveal both the site of the retinal interaction and the underlying mechanism.
    1. Neuroscience
    2. Physics of Living Systems

    Binocular rivalry reveals an out-of-equilibrium neural dynamics suited for decision-making

    Robin Cao, Alexander Pastukhov ... Jochen Braun
    The statistics of binocular rivalry at different combinations of image contrast is reproduced quantitatively by competing out-of-equilibrium populations of independent neural assemblies with idealized attractor dynamics.
    1. Cell Biology

    Mitochondrial flashes regulate ATP homeostasis in the heart

    Xianhua Wang, Xing Zhang ... Heping Cheng
    Mitochondrial flashes counteract the imbalance of ATP supply-and-demand and constitute an auto-regulator of ATP homeostasis in the heart.
    1. Neuroscience

    Control of voluntary and optogenetically perturbed locomotion by spike rate and timing of neurons of the mouse cerebellar nuclei

    Rashmi Sarnaik, Indira M Raman
    Stride-related modulated firing by neurons of the cerebellar nuclei is required for smooth execution of practiced locomotion and persists more easily with synchronous than asynchronous Purkinje-mediated inhibition.
    1. Cancer Biology
    2. Genetics and Genomics

    DUX4 is a common driver of immune evasion and immunotherapy failure in metastatic cancers

    Jose Mario Bello Pineda, Robert K Bradley
    DUX4 expression is a common feature of metastatic tumors, where it is significantly associated with immune cell exclusion, decreased objective response to immune checkpoint blockade, and reduced patient survival.
    1. Neuroscience

    Range, routing and kinetics of rod signaling in primate retina

    William N Grimes, Jacob Baudin ... Fred Rieke
    Signals from primate rod photoreceptors do not exhibit the light-level-dependent routing through parallel retinal circuits observed in rodents and often invoked in interpreting psychophysical experiments.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Phospholipase D activity couples plasma membrane endocytosis with retromer dependent recycling

    Rajan Thakur, Aniruddha Panda ... Padinjat Raghu
    Phosphatidic acid regulates recycling of endocytosed plasma membrane vesicles in polarized cells through a retromer and Arf1 dependent process.

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