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Comparisons of enzyme efficiency and electron transfer show that, to oxidize water using lower energy light, the two types of far-red photosystem II have adopted opposite trade-offs between efficiency of light use and resilience to light damage.

Sensations arising from internal organs like the heart can affect how the brain decides between two mutually incompatible perceptions of the same visual stimulus.

A series of experiments suggest that the fronto-parietal attentional network is involved in controlling eye-based attention, and FEF plays a crucial causal role in generating the attention-induced ocular dominance shift.

TRIM28 was found to be a versatile dual-function latency contributor by bridging both suppressive epigenetic modifications and RNAP II transcriptional-pausing, and can be a novel target to develop latency-reversing agents.

ESCRT-III heteropolymers utilize non-specific lateral electrostatic interactions to recognize one another, which may enable the polymers to slide along one another and adapt to different curvatures.

Colon cancer cells disseminate and colonize distant organ sites along the invasion-metastasis cascade by transiently activating intermediate epithelial to mesenchymal transition states through distinct transcriptional trajectories.

To improve the reliability of transmitting small single-photon voltage responses, rod photoreceptor cells release synaptic vesicles in regularly timed multivesicular events that are exquisitely sensitive to small voltage changes.

Targeted mutations in a Ca²⁺-binding site of otoferlin, a transmembrane protein of synaptic vesicles defective in a recessive form of deafness, reveal its Ca²⁺ sensor role both for vesicle fusion and vesicle pool replenishment.

Structural and biochemical analysis of an abundant and conserved protein complex called EMC shows how it is likely to insert nascent membrane proteins into the endoplasmic reticulum membrane.