635 results found
    1. Developmental Biology

    A phenotypic screening platform utilising human spermatozoa identifies compounds with contraceptive activity

    Franz S Gruber et al.
    A high-throughput phenotypic human sperm screening platform was developed which allows for major drug discovery programmes for male contraception.
    1. Cell Biology

    Axial contraction and short-range compaction of chromatin synergistically promote mitotic chromosome condensation

    Tom Kruitwagen et al.
    Condensation and segregation of chromosomes during mitosis is caused by a combination of short-range interactions between nucleosomes and the long-range contraction of chromosome arms mediated by condensin.
    1. Computational and Systems Biology

    Active contraction of microtubule networks

    Peter J Foster et al.
    Microtubule networks in frog egg extracts can spontaneously contract in a manner that can be quantitatively described by an active fluid model.
    1. Cell Biology

    An adaptation of astronomical image processing enables characterization and functional 3D mapping of individual sites of excitation-contraction coupling in rat cardiac muscle

    Qinghai Tian et al.
    The fusion of astronomy and cellular cardiology reveals the 3D arrangement and the firing reliability of active excitation-contraction coupling sites in beating cardiac myocytes.
    1. Cell Biology

    Curvature-induced expulsion of actomyosin bundles during cytokinetic ring contraction

    Junqi Huang et al.
    Cytokinetic actomyosin ring disassembly occurs through a novel mechanism in which the increased ring curvature, generated through contraction, itself promotes the disassembly process.
    1. Developmental Biology

    Muscle contraction is required to maintain the pool of muscle progenitors via YAP and NOTCH during fetal myogenesis

    Joana Esteves de Lima et al.
    A novel mechanism links mechanical signals with the molecular YAP and NOTCH signals operating during developmental myogenesis.
    1. Neuroscience

    A circuit mechanism for the propagation of waves of muscle contraction in Drosophila

    Akira Fushiki et al.
    Coordinated activation and deactivation of inhibitory neurons triggers sequential muscle contractions that enable fruit fly larvae to propel themselves backwards and forwards.
    1. Cell Biology
    2. Physics of Living Systems

    Centering and symmetry breaking in confined contracting actomyosin networks

    Niv Ierushalmi et al.
    Novel mechanisms for cellular centering and symmetry breaking involving persistent contractile actomyosin flows and their hydrodynamic interactions with the fluid cytosol are presented and studied using a minimal, reconstituted system.
    1. Cell Biology
    2. Physics of Living Systems

    Graded titin cleavage progressively reduces tension and uncovers the source of A-band stability in contracting muscle

    Yong Li et al.
    Elastic forces generated by the giant protein titin define both passive and active tension of skeletal muscle fibers and protect the sarcomeric myosin filaments from severe disruption during contraction.
    1. Cell Biology

    Cytokinesis in vertebrate cells initiates by contraction of an equatorial actomyosin network composed of randomly oriented filaments

    Felix Spira et al.
    Asymmetric tension increase along the cell equator promotes self-organization of actomyosin into a partially aligned network during cytokinetic cleavage furrow ingression of vertebrate cells.

Refine your results by:

Type
Research categories