305 results found
    1. Human Biology and Medicine

    Bioengineered human myobundles mimic clinical responses of skeletal muscle to drugs

    Lauran Madden et al.
    A novel bioengineered human skeletal muscle model with accurate physiological and pharmacological responses may provide a useful tool for preclinical testing.
    1. Human Biology and Medicine

    Tissue Engineering: Muscling in on the third dimension

    Mohsen Afshar Bakooshli, Penney M Gilbert
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    1. Cancer Biology
    2. Cell Biology

    Cell Proliferation: The ROCKs on which tumour cells thrive

    Simon Wilkinson, Margaret C Frame
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    1. Human Biology and Medicine
    2. Neuroscience

    Point of View: Predictive regulation and human design

    Peter Sterling
    Why does the human regulatory system, which evolution tuned for small satisfactions, now constantly demand 'more'?
    1. Cell Biology
    2. Developmental Biology

    Mechanotransduction: How muscle contraction strengthens tendons

    Nicole O Glenn, Clarissa A Henry
    The force generated by muscles leads to signaling that helps to shape nearby tendon precursor cells.
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    1. Cell Biology
    2. Evolutionary Biology

    Multicellularity: How contraction has shaped evolution

    Mukund Thattai
    Two new unicellular organisms reveal that coordinated contractions of groups of cells using actomyosin predated animal multicellularity during evolution.
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    1. Cell Biology
    2. Human Biology and Medicine

    Muscle Contraction: Too much of a good thing

    H Lee Sweeney
    A mutation that causes heart disease in humans increases the number of active myosin heads during contraction in the muscles of fruit flies, leading to the progressive dysfunction of the flight muscles and heart tube.
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    1. Neuroscience

    Acute intermittent hypoxia enhances corticospinal synaptic plasticity in humans

    Lasse Christiansen et al.
    Acute intermittent hypoxia is a noninvasive approach that enhances corticospinal function in humans, likely through alterations in corticospinal-motoneuronal synaptic transmission.
    1. Cell Biology

    The fibronectin synergy site re-enforces cell adhesion and mediates a crosstalk between integrin classes

    Maria Benito-Jardón et al.
    The fibronectin synergy site is only required in vivo when forces exceed or αvβ3 integrin levels fall below certain thresholds.
    1. Computational and Systems Biology
    2. Neuroscience

    Microsaccadic sampling of moving image information provides Drosophila hyperacute vision

    Mikko Juusola et al.
    New experiments and theory reveal how the ability to see image details depends upon photoreceptor function and eye movements, and how fruit flies (Drosophila) see spatial details beyond the optical limit of their compound eyes.

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