3,076 results found
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    T cell receptor convergence is an indicator of antigen-specific T cell response in cancer immunotherapies

    Mingyao Pan, Bo Li
    Amino acid codon degeneracy indicates antigen-specific selection of the T cell receptors and is predictive of cancer immunotherapy outcomes.
    1. Developmental Biology
    2. Structural Biology and Molecular Biophysics

    Large, long range tensile forces drive convergence during Xenopus blastopore closure and body axis elongation

    David R Shook, Eric M Kasprowicz ... Raymond Keller
    Blastopore closure in Xenopus is driven by two morphogenic mechanisms that have strongly context dependent effects on tissue movement and that generate tensile force across tissues: convergent extension, as expected, and, unexpectedly, convergent thickening.
    1. Ecology
    2. Evolutionary Biology

    Convergence between the microcosms of Southeast Asian and North American pitcher plants

    Leonora S Bittleston, Charles J Wolock ... Anne Pringle
    Host characteristics drive the assembly of similar communities within the convergently evolved and geographically distant pitcher ecosystems of carnivorous pitcher plants.
    1. Cancer Biology
    2. Genetics and Genomics

    Convergent epigenetic evolution drives relapse in acute myeloid leukemia

    Kevin Nuno, Armon Azizi ... Ravindra Majeti
    Integrated analyses of acute myeloid leukemia genetics and epigenetics demonstrate that epigenetic evolution occurs in a convergent manner in the absence of DNA mutations at relapse post-chemotherapy.
    1. Ecology
    2. Evolutionary Biology

    Mimicry can drive convergence in structural and light transmission features of transparent wings in Lepidoptera

    Charline Sophie Pinna, Maëlle Vilbert ... Marianne Elias
    Wing transparency in mimetic butterflies and moths is achieved by an unexpected diversity of structural features, and both structures and light transmission properties of wings are under selection for convergence.
    1. Developmental Biology
    2. Plant Biology

    Formation of polarity convergences underlying shoot outgrowths

    Katie Abley, Susanna Sauret-Güeto ... Enrico Coen
    Models that generate tandem alignments of cell polarities are more readily compatible with the formation of PIN1 polarity patterns in plant leaf buds than the most widely accepted “up-the-gradient” model.
    1. Developmental Biology
    2. Physics of Living Systems

    Characterization of convergent thickening, a major convergence force producing morphogenic movement in amphibians

    David R Shook, Jason WH Wen ... Ray E Keller
    Xenopus embryos use tissue surface tension to generate hoop-stress around the blastopore to help close it during gastrulation.
    1. Neuroscience

    A task-general connectivity model reveals variation in convergence of cortical inputs to functional regions of the cerebellum

    Maedbh King, Ladan Shahshahani ... Jörn Diedrichsen
    Models of cortico-cerebellar connectivity are quantified using task-based fMRI, and demonstrate that convergent rather than sparse inputs best characterize cortico-cerebellar connectivity, namely, cerebellar areas linked to cognition receive the highest convergence of cortical inputs.
    1. Evolutionary Biology

    Myoglobin primary structure reveals multiple convergent transitions to semi-aquatic life in the world's smallest mammalian divers

    Kai He, Triston G Eastman ... Kevin L Campbell
    Ancestral sequence reconstruction of an essential muscle protein involved in oxygen storage and transport accurately tracks secondary aquatic transitions in a speciose clade of insectivorous mammals.
    1. Developmental Biology

    Nodal and planar cell polarity signaling cooperate to regulate zebrafish convergence and extension gastrulation movements

    Margot LK Williams, Lilianna Solnica-Krezel
    Nodal signaling regulates gastrulation cell behaviors largely in parallel with planar cell polarity signaling and is sufficient for ex vivo extension of embryonic explants.

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