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    1. Genetics and Genomics
    2. Neuroscience

    Reorganization of postmitotic neuronal chromatin accessibility for maturation of serotonergic identity

    Xinrui L Zhang, William C Spencer ... Evan S Deneris
    Terminal selectors reorganize postmitotic neuronal chromatin to select cis-regulatory elements during 5-HT neuron maturation.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    AP-2α and AP-2β cooperatively function in the craniofacial surface ectoderm to regulate chromatin and gene expression dynamics during facial development

    Eric Van Otterloo, Isaac Milanda ... Trevor Williams
    In addition to a neural crest cell specific role, AP-2α and AP-2ß cooperatively promote craniofacial development through regulating chromatin and gene expression dynamics in the facial surface ectoderm.
    1. Ecology

    Testosterone pulses paired with a location induce a place preference to the nest of a monogamous mouse under field conditions

    Radmila Petric, Matina Kalcounis-Rueppell, Catherine A Marler
    Transient increases in the hormone testosterone shift behavioral focus by influencing both spatial preference and vocalizations of a monogamous and biparental mouse in the wild.
    1. Ecology
    2. Evolutionary Biology

    Experimental evidence for delayed post-conflict management behaviour in wild dwarf mongooses

    Amy Morris-Drake, Julie M Kern, Andrew N Radford
    After experimentally simulated within-group conflict, dwarf mongoose bystanders engage in post-conflict management behaviour with a temporal delay.
    1. Ecology

    Little evidence that Eurasian jays protect their caches by responding to cues about a conspecific’s desire and visual perspective

    Piero Amodio, Benjamin G Farrar ... Nicola S Clayton
    Across five experiments, Eurasian jays’ caching behaviour provides little evidence of the ability to integrate cues about a potential pilferer’s visual perspective and desire and, challenging previous findings, to respond to either of the two social cues independently.
    1. Ecology
    2. Evolutionary Biology

    Living with relatives offsets the harm caused by pathogens in natural populations

    Hanna M Bensch, Emily A O'Connor, Charlie Kinahan Cornwallis
    Experiments show that pathogens spread more easily among relatives causing increased mortality, but such costs are cancelled out by the benefits of living with kin when pathogens are rare.
    1. Cell Biology
    2. Neuroscience

    Functional interdependence of the actin nucleator Cobl and Cobl-like in dendritic arbor development

    Maryam Izadi, Eric Seemann ... Michael M Kessels
    Extended biochemical and functional analyses in primary neurons show that early neuronal morphogenesis critically relies on cooperation of the actin nucleator Cobl and its ancestor Cobl-like and uncover their cooperative mechanisms at dendritic branch initiation sites.
    1. Neuroscience

    Dorsal raphe nucleus to anterior cingulate cortex 5-HTergic neural circuit modulates consolation and sociability

    Laifu Li, Li-Zi Zhang ... Fa-Dao Tai
    Inhibition of 5-HT neurons in the dorsal raphe nuclei or 5-HT terminals in the anterior cingulate cortex decreased consolation-like behaviors and reduced sociability.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    A sustained type I IFN-neutrophil-IL-18 axis drives pathology during mucosal viral infection

    Tania Lebratti, Ying Shiang Lim ... Haina Shin
    Type I IFN is a key determinant of pathogenic neutrophil activity and drives tissue pathology through modulation of IL-18 levels during genital HSV infection.
    1. Evolutionary Biology
    2. Immunology and Inflammation

    Glycan-based shaping of the microbiota during primate evolution

    Sumnima Singh, Patricia Bastos-Amador ... Miguel P Soares
    Ggta1 deletion in mice shapes and reduces the microbiota pathogenicity and probably contributed to the natural selection of GGTA1 loss-of-function mutations in the ancestral primates that gave rise to humans.