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Vglut2-based glutamatergic signaling in central noradrenergic neurons is dispensable for baseline breathing and hypercapnic, hypoxic chemosensory reflexes, which challenges the current understanding of central noradrenergic neurons in breathing control.

The timing and outcome of mammalian cell lineage decisions can be controlled by slow, stochastic events on individual regulatory gene loci.

The Hedgehog signalling pathway is a master regulator of lipid metabolic processes and their zonation in the adult liver of mice and humans.

Pacemaker neurons are present in the preBötC circuitry of mouse embryos and their role in driving respiratory network activity changes during the critical period immediately before birth.

Deactivation of one side of the auditory midbrain while recording in the other shows that the two sides cooperate in processing frequency and in enhancing the encoding of sound level.

The myogenic lineage transcription factor, MYOD1, amplifies and works with the core clock factors to support a daily muscle gene expression program.

Type I IFN is a key determinant of pathogenic neutrophil activity and drives tissue pathology through modulation of IL-18 levels during genital HSV infection.

The midbrain periaqueductal grey is a conserved mediator of elaborate courtship behavior in a range of vertebrate taxa, likely shaping how this behavior diversifies across the tree of life.

Inhibiting KRAS^G12C and ULK-mediated autophagy is a novel treatment strategy to control the growth of KRAS^G12C-driven lung cancer in preclinical models of lung cancer.