In feedforward networks with random connectivity, connection motifs underlying the detection of short clusters and activity sequences are likely to converge on a subset of postsynaptic neurons purely by chance.

Computational pipeline SPICE systematically screens and predicts novel protein-protein binding complexes including the previously unrecognized global association and functional cooperation between IKZF1 and AP1.

Social clustering behaviors in Drosophila are closely tied to compensatory mechanisms for developmental traits and adaptive behavior plasticity, requiring early-life social experiences and the memory-encoding neuropeptide signaling pathway.