53 results found
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Scrutinized lipid utilization disrupts Amphotericin-B responsiveness in clinical isolates of Leishmania donovani

    Supratim Pradhan, Dhruba Dhar ... Budhaditya Mukherjee
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Bacterial death and TRADD-N domains help define novel apoptosis and immunity mechanisms shared by prokaryotes and metazoans

    Gurmeet Kaur, Lakshminarayan M Iyer ... L Aravind
    Prokaryotic TRADD-N and Death-like adaptor domains in diverse predicted apoptosis and immune systems from multicellular prokaryotes and metazoans indicate the common origin of key apoptosis mechanisms required for the stabilization of multicellularity.
    1. Biochemistry and Chemical Biology

    Regulated mRNA recruitment in dinoflagellates is reflected in hyper-variable mRNA spliced leaders and novel eIF4Es

    Grant D. Jones, Ernest P. Williams ... Rosemary Jagus
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Developmental Biology
    2. Evolutionary Biology

    Bacterial contribution to genesis of the novel germ line determinant oskar

    Leo Blondel, Tamsin EM Jones, Cassandra G Extavour
    Evidence suggests that the oskar gene, a critical germ line determinant in insects, was formed by fusion of bacterial and eukaryotic sequences at least 450 million years ago.
    1. Evolutionary Biology

    A direct experimental test of Ohno’s hypothesis

    Ljiljana Mihajlovic, Bharat Ravi Iyengar ... Yolanda Schaerli
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Intraspecific predator interference promotes biodiversity in ecosystems

    Ju Kang, Shijie Zhang ... Xin Wang
    Intraspecific predator interference enables a wide range of consumer species to coexist with a limited variety of resources, explaining the paradox of the plankton and species diversity patterns across ecosystems.
    1. Cell Biology

    Atlas of Fshr expression from novel reporter mice

    Hongqian Chen, Hui-Qing Fang ... Peng Liu
    Exploiting the power of the Fshr reporter, the first comprehensive genetic record of the spatial distribution of FSHR expression offers prospects for extensive exploration of FSH-FSHR biology.
    1. Microbiology and Infectious Disease

    Interactions between metabolism and growth can determine the co-existence of Staphylococcus aureus and Pseudomonas aeruginosa

    Camryn Pajon, Marla C Fortoul ... Robert P Smith
    The growth environment driven ratio of ATP to growth rate, called absolute growth, determines the final population composition of Staphylococcus aureus and Pseudomonas aeruginosa when in co-culture.
    1. Ecology

    Experimental evidence that chronic outgroup conflict reduces reproductive success in a cooperatively breeding fish

    Ines Braga Goncalves, Andrew N Radford
    Outgroup conflict can negatively impact general reproductive behaviour, egg investment, and parental care, resulting in decreased reproductive output even in the absence of physical confrontations.
    1. Genetics and Genomics

    Environmentally-induced epigenetic conversion of a piRNA cluster

    Karine Casier, Valérie Delmarre ... Antoine Boivin
    Activation of a piRNA cluster is achieved by high temperature and without maternal inheritance of homologous piRNAs highlighting how variations of species natural habitat can become heritable and shape epigenome.

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