Epigenetic regulations in the smoking- and blood pressure-related pathways to the future risk of coronary heart disease may reveal novel pathways or therapeutic targets.

Genetic data from siblings provides strong evidence that taller height increases the risk of cancers but lowers the risk of coronary disease.

Lifestyle interventions and statins may target different components of the lipid profile, suggesting that they are not redundant strategies but could be combined for better benefits.

In a prospective, population-based cohort, high polygenic risk and infection with Fusobacterium nucleatum have a small, yet independent impact on coronary heart disease risk.

During the evolution of amniotes, the transformation of branchial arches coincided with the drastic remodeling of the ancestral extrinsic cardiac arteries, giving rise to novel ventricular coronary arteries that are unique to amniotes.

Comprehensive decade-long analysis of point-of-care resources reveals insights into how clinical research makes its way into practice across different medical specialties and through time to enable us to identify potential translational bottlenecks in the pathway from research to practice.

Progenitor cells for the muscle layer around the coronary arteries have been identified revealing a key step in how the embryo forms these important blood vessels.

Using genetics, it is possible to uncouple higher adiposity from its adverse metabolic effects and show that some obesity-associated conditions may benefit from treating the metabolic effects alone, whilst others may benefit more from weight loss.

SARS-CoV-2 infection in hamsters causes cardiovascular pathologies.

A comprehensive resource to systematically evaluate the genetically predicted associations between 125 polygenic risk scores and 249 metabolic traits.