60 results found
    1. Epidemiology and Global Health
    2. Neuroscience

    Neuropathogenesis of SARS-CoV-2 infection

    Shumayila Khan, James Gomes
    Clinical data of SARS-CoV-2 patients presenting atypical symptoms must be recorded systematically to support continuing research investigating neurological complications associated with COVID-19.
    1. Epidemiology and Global Health

    Evidence for transmission of COVID-19 prior to symptom onset

    Lauren C Tindale et al.
    Control of COVID-19 will require strong case finding and isolation of exposed individuals because transmission can occur days prior to symptom onset.
  1. CoVis: discover relibale COVID-19 research

    CoVis: a new tool to discover reliable COVID-19 research

    CoVis is a community-driven resource to help scientists kick-start their COVID-19 research.
    1. Human Biology and Medicine

    Knowledge synthesis of 100 million biomedical documents augments the deep expression profiling of coronavirus receptors

    AJ Venkatakrishnan et al.
    SARS-CoV-2 receptor ACE2 is expressed in nasal olfactory epithelia, tongue keratinocytes and small intestine enterocytes, connected with the COVID-19 patient phenotypes such as anosmia and diarrhea.
    1. Genetics and Genomics
    2. Human Biology and Medicine

    Does the human placenta express the canonical cell entry mediators for SARS-CoV-2?

    Roger Pique-Regi et al.
    The human placenta negligibly co-expresses the transcripts encoding the canonical cell-entry mediators for SARS-CoV-2, which explains why mothers with COVID-19 rarely transmit the virus to the fetus.
    1. Immunology and Inflammation

    CARD14E138A signalling in keratinocytes induces TNF-dependent skin and systemic inflammation

    Joan Manils et al.
    Expression of a psoriasis-associated CARD14E138A mutant in keratinocytes induces TNF-dependent localised skin and systemic inflammation independently of the adaptive immune system.
    1. Computational and Systems Biology
    2. Human Biology and Medicine

    SARS-CoV-2 strategically mimics proteolytic activation of human ENaC

    Praveen Anand et al.
    SARS-CoV-2 has evolved to cleverly mimic the FURIN-cleavage site in human ENaC-α, unlike any prior coronavirus strain, shedding new light on the Acute Respiratory Distress Syndrome (ARDS) in COVID-19 patients.
    1. Epidemiology and Global Health
    2. Human Biology and Medicine

    Effective control of SARS-CoV-2 transmission between healthcare workers during a period of diminished community prevalence of COVID-19

    Nick K Jones et al.
    Diminished incidence of COVID-19 amongst healthcare workers in a comprehensive screening programme demonstrates how effective infection control measures and staff testing can prevent hospitals becoming independent 'hubs' of SARS-CoV-2 transmission.
    1. Epidemiology and Global Health
    2. Human Biology and Medicine

    Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission

    Lucy Rivett et al.
    3% of >1,000 asymptomatic healthcare workers in their workplace tested positive for SARS-CoV-2, suggesting that comprehensive screening programmes are vital to prevent acquisition of COVID-19 in hospitals.

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