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6,009 results found
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    SET-9 and SET-26 are H3K4me3 readers and play critical roles in germline development and longevity

    Wenke Wang et al.
    Two SET-domain containing proteins regulate H3K4me3 by their binding to H3K4me3 through their PHD domain and directly regulate expression of a subset of genes.
    1. Developmental Biology
    2. Neuroscience

    Synaptic and intrinsic mechanisms underlying development of cortical direction selectivity

    Arani Roy et al.
    The development of neural responses proceeds through both the expansion and contraction of receptive field structure, and in addition depends upon changes in excitability of individual cells.
    1. Neuroscience

    Developmental deprivation-induced perceptual and cortical processing deficits in awake-behaving animals

    Justin D Yao, Dan H Sanes
    Developmental hearing loss causes perceptual deficits that are best explained by degraded auditory cortical encoding that is recorded during task performance.
    1. Developmental Biology
    2. Neuroscience

    GSK-3 signaling in developing cortical neurons is essential for radial migration and dendritic orientation

    Meghan Morgan-Smith et al.
    The kinase GSK-3 regulates cortical neuronal migration and dendritic orientation by phosphorylating key cytoskeletal proteins.
    1. Cell Biology
    2. Developmental Biology

    miR-128 regulates neuronal migration, outgrowth and intrinsic excitability via the intellectual disability gene Phf6

    Eleonora Franzoni et al.
    The regulation of Phf6 by miR-128 is a developmental timing mechanism that influences cortical lamination, neuronal morphology and intrinsic excitability.
    1. Developmental Biology
    2. Neuroscience

    Dentate gyrus development requires a cortical hem-derived astrocytic scaffold

    Alessia Caramello et al.
    An astrocytic scaffold that depends on SOX9 guides embryonic neuronal progenitors toward the developing dentate gyrus.
    1. Neuroscience

    Development of visual motion integration involves coordination of multiple cortical stages

    Augusto A Lempel, Kristina J Nielsen
    The development of complex motion processing in higher-level visual cortex involves functional changes in primary visual cortex, indicating coordinated development in multiple nodes of the visual hierarchy.
    1. Developmental Biology
    2. Neuroscience

    Shifts in myeloarchitecture characterise adolescent development of cortical gradients

    Casey Paquola et al.
    Layer-specific microstructural changes contribute to the maturation of cortical organisation during adolescence.
    1. Developmental Biology

    A transient role of the ciliary gene Inpp5e in controlling direct versus indirect neurogenesis in cortical development

    Kerstin Hasenpusch-Theil et al.
    Primary-cilia-mediated processing of the Gli3 transcription factor enables the formation of subtypes of projection neurons in appropriate numbers during the development of the cerebral cortex.
    1. Neuroscience

    Maternal cortisol is associated with neonatal amygdala microstructure and connectivity in a sexually dimorphic manner

    David Q Stoye et al.
    Prenatal stress is transmitted to infant development through cortisol, which imparts sex-specific effects on the development and connectivity of the amygdalae.

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