Two major subtypes of cortical interneurons, the PV and the SST positive cells, causally contribute to the regulation of large-scale state transitions in the cortex.

A-type potassium conductances influence the distinctive firing behaviour of irregular-spiking interneurons.

Two genetically distinct Stxbp1 haploinsufficiency mouse models exhibit seizures and impairments in cognitive, psychiatric, and motor functions, representing robust preclinical models of STXBP1 encephalopathy with both construct and face validity.

In the visual system, three rules guide the thalamocortical connectivity of cortical fast-spike interneurons and are key to understand the potent and broadly tuned feed-forward inhibition that they generate.

A fast spiking interneuron sub-type in medial and lateral prefrontal cortex fires and gamma-synchronizes prominently during adaptive learning of reward values when outcomes are uncertain and choice options have similar values.

The synaptic structure in mouse V1 is explained by a synergy of homeostatic plasticity in incoming and outgoing synapses of inhibitory interneurons, establishing a stimulus-specific balance of excitation and inhibition.

Accumulation of perineuronal nets around parvalbumin (PV)-positive inhibitory interneurons closes visual cortical plasticity by selectively down-regulating thalamic synapses onto PV cells in a sensory-dependent manner.

Two distinct types of inhibitory neurons increase the brain's sensitivity to unexpected acoustic signals by amplifying selective suppression of cortical responses to frequent, but not rare sounds.

Id2 GABAergic interneurons represent a fourth major group of local inhibitory neurons that includes neurogliaform cells, and these neurons can be targeted using intersectional genetics, revealing their distinctive connectivity and in vivo activity properties.

VIP-expressing cortical interneurons represent organism-level information about reward and punishment for local microcircuits to regulate local processing and plasticity.