1,613 results found
    1. Neuroscience

    All-trans retinoic acid induces synaptic plasticity in human cortical neurons

    Maximilian Lenz et al.
    The vitamin A derivative, all-trans retinoic acid, induces protein-synthesis-dependent synaptic plasticity in the human brain.
    1. Neuroscience

    A cortical disinhibitory circuit for enhancing adult plasticity

    Yu Fu et al.
    Building on previous work (Kaneko and Stryker, 2014), we report that the specific population of inhibitory neurons that increases the responses of neurons in the visual cortex during locomotion will also, when activated or blocked artificially, dramatically alter adult cortical plasticity, revealing that the aerobic exercise of locomotion is not necessary.
    1. Neuroscience

    Translational control of auditory imprinting and structural plasticity by eIF2α

    Gervasio Batista et al.
    Behavioral pharmacology and molecular biology reveal a translational control mechanism underlying auditory imprinting and structural plasticity that can be pharmacologically manipulated to reopen the critical period.
    1. Neuroscience

    Pull-push neuromodulation of cortical plasticity enables rapid bi-directional shifts in ocular dominance

    Su Z Hong et al.
    Neuromodulation of the expression of Hebbian plasticity enables rapid cortical sensory-induced remodeling in post-critical period adults, and can rescue deficits induced by prolonged sensory deprivation.
    1. Neuroscience

    Optimal level activity of matrix metalloproteinases is critical for adult visual plasticity in the healthy and stroke-affected brain

    Justyna Pielecka-Fortuna et al.
    Matrix metalloproteinases play a crucial role in adult visual plasticity in the brains of healthy and stroke-affected mice and their activity has to be within a narrow window for experience-induced plasticity to occur.
    1. Neuroscience

    Perineuronal nets control visual input via thalamic recruitment of cortical PV interneurons

    Giulia Faini et al.
    Accumulation of perineuronal nets around parvalbumin (PV)-positive inhibitory interneurons closes visual cortical plasticity by selectively down-regulating thalamic synapses onto PV cells in a sensory-dependent manner.
    1. Neuroscience

    CCR5 is a suppressor for cortical plasticity and hippocampal learning and memory

    Miou Zhou et al.
    Repression of the G protein-coupled chemokine receptor CCR5 enhances MAPK/CREB signaling, long-term potentiation, somatosensory cortical plasticity, and learning and memory, while CCR5 over-activation by viral proteins may contribute to HIV-associated cognitive deficits.
    1. Computational and Systems Biology
    2. Neuroscience

    A unified computational model for cortical post-synaptic plasticity

    Tuomo Mäki-Marttunen et al.
    Biochemically detailed modelling of pathways leading to post-synaptic plasticity reveals the dependence of neocortical LTP/LTD on the availability of different proteins and stimulation patterns.
    1. Neuroscience

    Contrasting roles for parvalbumin-expressing inhibitory neurons in two forms of adult visual cortical plasticity

    Eitan S Kaplan et al.
    Parvalbumin-containing inhibitory neurons are crucial for expression of plasticity in adult visual cortex that supports visual recognition memory, but not for expression of ocular dominance plasticity that results from monocular deprivation.
    1. Neuroscience

    A Toll-receptor map underlies structural brain plasticity

    Guiyi Li et al.
    Structural brain plasticity is encoded in the topographic distribution of Toll receptors and their ability to switch between alternative signalling outcomes, thus translating diverse sensory experience into structural change.

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