661 results found
    1. Neuroscience

    Transcriptomics-informed large-scale cortical model captures topography of pharmacological neuroimaging effects of LSD

    Joshua B Burt, Katrin H Preller ... John D Murray
    Computational models of large-scale cortical dynamics, integrating gene expression mapping to pattern pharmacological modulation across cortex, capture inter-areal topographies of functional connectivity alterations induced by lysergic acid diethylamide, providing a framework for simulating effects of pharmacology in the human brain.
    1. Neuroscience

    Complex pattern of facial remapping in somatosensory cortex following congenital but not acquired hand loss

    Victoria Root, Dollyane Muret ... Tamar R Makin
    Both hand and face representations remain relatively stable after arm amputation in adulthood, with no link to phantom limb pain, whereas pre-natal limb loss triggers complex patterns of remapping that do not relate to cortical topography.
    1. Neuroscience

    Adaptation of spontaneous activity in the developing visual cortex

    Marina E Wosniack, Jan H Kirchner ... Julijana Gjorgjieva
    To generate stable and robust connectivity refinements, the amplitude of spontaneous activity events in the developing visual cortex adapts to the recent history of cortical activation.
    1. Neuroscience

    Signal denoising through topographic modularity of neural circuits

    Barna Zajzon, David Dahmen ... Renato Duarte
    Topographic maps can gradually increase the fidelity of sensory representations and improve signal-to-noise ratio across multiple cortical circuits, a generic architectural feature that depends solely on the modularity of topographic projections and recurrent inhibition.
    1. Neuroscience

    The neural basis of intelligence in fine-grained cortical topographies

    Ma Feilong, J Swaroop Guntupalli, James V Haxby
    Individual differences in intelligence are based on information processing that is embedded in fine-scale structure in cortical systems for self-generated thought, which was revealed by resolving topographic idiosyncrasies with hyperalignment.
    1. Neuroscience

    Widespread correlation patterns of fMRI signal across visual cortex reflect eccentricity organization

    Michael J Arcaro, Christopher J Honey ... Uri Hasson
    Functional coupling between visual areas reflects supra-areal eccentricity organization distinct from overlapping receptive field connectivity during both rest conditions and naturalistic movie viewing.
    1. Neuroscience

    The organizational principles of de-differentiated topographic maps in somatosensory cortex

    Peng Liu, Anastasia Chrysidou ... Esther Kuehn
    SI topographic finger maps of older adults show signs of cortical aging but do not show classical hallmarks of cortical de-differentiation.
    1. Neuroscience

    Revealing the neural fingerprints of a missing hand

    Sanne Kikkert, James Kolasinski ... Tamar R Makin
    The brain continues to represent individual fingers in primary somatosensory cortex decades after the amputation of a hand, indicating that cortical maps do not require ongoing sensory input from the body.
    1. Neuroscience

    The relationship between spatial configuration and functional connectivity of brain regions

    Janine Diane Bijsterbosch, Mark W Woolrich ... Stephen M Smith
    Connectivity network matrices, as estimated with masking or dual regression against group-level parcellations, reflect little or no unique cross-subject information that is not also captured by spatial topographical variability.
    1. Computational and Systems Biology
    2. Neuroscience

    A molecular mechanism for the topographic alignment of convergent neural maps

    Elise Savier, Stephen J Eglen ... Michael Reber
    Retinal ephrin-As gradients provide positional information, through retino-collicular map in the superior colliculus, for topographic alignment of cortico-collicular projections.

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