127 results found
    1. Neuroscience

    An open cortico-basal ganglia loop allows limbic control over motor output via the nigrothalamic pathway

    Sho Aoki, Jared B Smith ... Xin Jin
    A novel connection from ventral striatum to motor cortex enables emotion and motivation to influence action and motor control.
    1. Neuroscience

    Neural activity in cortico-basal ganglia circuits of juvenile songbirds encodes performance during goal-directed learning

    Jennifer M Achiro, John Shen, Sarah W Bottjer
    Activity in cortico-basal ganglia circuits of juvenile songbirds reflects evaluative signals necessary for comparing self-generated behavior to a goal representation during skill learning.
    1. Neuroscience

    M2 cortex-dorsolateral striatum stimulation reverses motor symptoms and synaptic deficits in Huntington’s disease

    Sara Fernández-García, Sara Conde-Berriozabal ... Mercè Masana
    M2 cortex-dorsolateral striatum circuit is functionally altered in Huntington's disease and, by boosting its activity, we reverse symptoms at behavioral, physiological, and morphological level in symptomatic mice.
    1. Neuroscience

    Motor cortex can directly drive the globus pallidus neurons in a projection neuron type-dependent manner in the rat

    Fuyuki Karube, Susumu Takahashi ... Fumino Fujiyama
    Globus pallidus neurons projecting to the striatum are preferentially activated by direct glutamatergic innervation from the motor cortex.
    1. Neuroscience

    Competing neural representations of choice shape evidence accumulation in humans

    Krista Bond, Javier Rasero ... Timothy Verstynen
    Interactions between cortical and subcortical circuits in the mammalian brain flexibly control the flow of information streams that drive decisions by shifting the balance of power both within and between action representations.
    1. Neuroscience

    A corticostriatal deficit promotes temporal distortion of automatic action in ageing

    Miriam Matamales, Zala Skrbis ... Jesus Bertran-Gonzalez
    Acquisition of behavioral sequences in normally aged mice involves short and unusually fast patterns of action, some of which are reproduced by striatal circuitry manipulations in young mice and can be transitorily restored through action-related feedback.
    1. Neuroscience

    A comprehensive excitatory input map of the striatum reveals novel functional organization

    Barbara J Hunnicutt, Bart C Jongbloets ... Tianyi Mao
    The first comprehensive map of all excitatory inputs to the mouse striatum is presented and used to define and demarcate striatal subdivisions, including a previous unappreciated novel subdivision in the posterior striatum.
    1. Neuroscience

    Movement-related coupling of human subthalamic nucleus spikes to cortical gamma

    Petra Fischer, Witold J Lipski ... R Mark Richardson
    When coupling between STN spikes and cortical gamma oscillations was strong, subsequent movement was initiated earlier, independent of changes in mean firing rates, demonstrating the importance of relative spike timing.
    1. Neuroscience

    Multi-study fMRI outlooks on subcortical BOLD responses in the stop-signal paradigm

    Scott Isherwood, Sarah A Kemp ... Birte Forstmann
    A novel meta-analytical method aggregating five SST datasets does not find evidence for the innervation of the hyperdirect or indirect cortico-basal-ganglia pathways in successful response inhibition.
    1. Neuroscience

    A subcortical circuit linking the cerebellum to the basal ganglia engaged in vocal learning

    Ludivine Pidoux, Pascale Le Blanc ... Arthur Leblois
    The cerebellum sends a functional input to the song-related basal ganglia via the thalamus in songbirds that can modify premotor activity, and it participates to song learning in juvenile birds.

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