136 results found
    1. Neuroscience

    Deprivation-related and use-dependent plasticity go hand in hand

    Tamar R Makin, Alona O Cramer ... Heidi Johansen-Berg
    In individuals with a missing hand, the area of the brain that would otherwise control that hand is recruited by either the remaining hand or the residual limb, depending on the usage preference of the individual.
    1. Neuroscience

    Regulation of branching dynamics by axon-intrinsic asymmetries in Tyrosine Kinase Receptor signaling

    Marlen Zschätzsch, Carlos Oliva ... Bassem A Hassan
    Asymmetric localization of the receptor EGFR within branches of axons is required to establish the precise wiring of neuronal networks within the Drosophila brain.
    1. Cell Biology
    2. Neuroscience

    Complete morphologies of basal forebrain cholinergic neurons in the mouse

    Hao Wu, John Williams, Jeremy Nathans
    The first complete 3D structures of mouse cholinergic neurons reveal the length and complexity of their axons, while calculations suggest that equivalent axons in the human brain are approximately than 100 meters long.
    1. Neuroscience

    Normalisation of brain connectivity through compensatory behaviour, despite congenital hand absence

    Avital Hahamy, Stamatios N Sotiropoulos ... Tamar R Makin
    Building on previous work (Makin et al., 2013), we show that the brains of individuals born without a hand adaptively change to compensate for their disability.
    1. Neuroscience

    Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity

    Isaac M Chiu, Lee B Barrett ... Clifford J Woolf
    Molecular analysis paints a detailed picture of the distinctiveness and complexities of peripheral somatosensory neurons.
    1. Neuroscience

    Causal manipulation of functional connectivity in a specific neural pathway during behaviour and at rest

    Vanessa M Johnen, Franz-Xaver Neubert ... Matthew F S Rushworth
    Functional connectivity in the human brain reflects changes in synaptic plasticity induced with repeated paired stimulation.
    1. Neuroscience

    Network structure of brain atrophy in de novo Parkinson's disease

    Yashar Zeighami, Miguel Ulla ... Alain Dagher
    The pattern of atrophy in Parkinson's disease is consistent with the disease spreading via intrinsic brain networks.
    1. Developmental Biology
    2. Neuroscience

    Genetic mechanisms control the linear scaling between related cortical primary and higher order sensory areas

    Andreas Zembrzycki, Adam M Stocker ... Dennis DM O'Leary
    Primary and higher order visual area dimensions in the neocortex are determined by the same genetic mechanisms during development which in turn also control the proportionate scaling between them.
    1. Developmental Biology
    2. Neuroscience

    Area-specific development of distinct projection neuron subclasses is regulated by postnatal epigenetic modifications

    Kawssar Harb, Elia Magrinelli ... Christian Alfano
    Lmo4 specifies two neuron subclasses in the mouse neocortex by promoting postnatal co-expression of the transcription factors Ctip2 and Satb2 via chromatin remodelling in a time and area-specific manner.
    1. Developmental Biology
    2. Neuroscience

    Layer specific and general requirements for ERK/MAPK signaling in the developing neocortex

    Lei Xing, Rylan S Larsen ... Jason M Newbern
    Aberrant ERK/MAPK signaling in cortical pyramidal neurons leads to selective disruption of layer 5 circuit development and generalized changes in neuronal excitability.

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