54 results found
    1. Neuroscience

    An inhibitory corticostriatal pathway

    Crystal Rock et al.
    The discovery of somatostatin-positive inhibitory neurons projecting from mouse cortex to striatum shows that corticostriatal pathways are not exclusively excitatory.
    1. Neuroscience

    A comprehensive excitatory input map of the striatum reveals novel functional organization

    Barbara J Hunnicutt et al.
    The first comprehensive map of all excitatory inputs to the mouse striatum is presented and used to define and demarcate striatal subdivisions, including a previous unappreciated novel subdivision in the posterior striatum.
    1. Neuroscience

    Secretagogin expression delineates functionally-specialized populations of striatal parvalbumin-containing interneurons

    Farid N Garas et al.
    In rodents and primates, there are two subtypes of parvalbumin-expressing interneurons that provide novel substrates for selective inhibition in the striatum.
    1. Neuroscience

    Neuromodulation of excitatory synaptogenesis in striatal development

    Yevgenia Kozorovitskiy et al.
    Protein kinase A regulates the rapid, activity-dependent genesis of excitatory synapses during striatal development.
    1. Neuroscience

    Medium spiny neurons activity reveals the discrete segregation of mouse dorsal striatum

    Javier Alegre-Cortés et al.
    Analysis of slow wave brain state unravels the functional connectivity and the biological substrate of the rodent dorsolateral and dorsomedial striatum, demonstrating its organization in two non-overlapping circuits.
    1. Neuroscience

    Disruption of Nrxn1α within excitatory forebrain circuits drives value-based dysfunction

    Opeyemi O Alabi et al.
    Disruption of the disease-associated synaptic adhesion molecule Neurexin1a in cortical excitatory neurons perturbs decision making and disrupts value-associated neural activity in downstream striatal circuits.
    1. Neuroscience

    Pauses in cholinergic interneuron firing exert an inhibitory control on striatal output in vivo

    Stefano Zucca et al.
    Optogenetics and in vivo recordings in mice reveal that pauses in cholinergic interneurons offer an alternative mechanism to inhibit subthreshold and suprathreshold events of spiny projection neurons.
    1. Neuroscience

    Corticostriatal dynamics encode the refinement of specific behavioral variability during skill learning

    Fernando J Santos et al.
    Recordings from the mouse brain as animals learn a lever pressing task reveal how the motor system optimizes skill learning by reducing variability in those aspects of task performance that are essential for achieving a goal.
    1. Neuroscience

    M2 cortex-dorsolateral striatum stimulation reverses motor symptoms and synaptic deficits in Huntington’s disease

    Sara Fernández-García et al.
    M2 cortex-dorsolateral striatum circuit is functionally altered in Huntington's disease and, by boosting its activity, we reverse symptoms at behavioral, physiological, and morphological level in symptomatic mice.
    1. Neuroscience

    Synapse-specific opioid modulation of thalamo-cortico-striatal circuits

    William T Birdsong et al.
    By differentially modulating the two major excitatory inputs to the striatum, mu- and delta-opioid receptors regulate the balance between thalamic and cortical inputs to the striatum.

Refine your results by:

Type
Research categories