121 results found
    1. Cell Biology

    AXONAL distribution of mitochondria maintains neuronal autophagy during aging via eIF2β

    Kanako Shinno, Yuri Miura ... Kanae Ando
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Biochemistry and Chemical Biology

    Elevated Ubiquitin Phosphorylation by PINK1 Contributes to Proteasomal Impairment and Promotes Neurodegeneration

    Cong Chen, Tong-Yao Gao ... Wei-Ping Zhang
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Developmental Biology

    The evolutionary modifications of a GoLoco motif in the AGS protein facilitate micromere formation in the sea urchin embryo

    Natsuko Emura, Florence DM Wavreil ... Mamiko Yajima
    Activator of G-protein signaling C-terminus serves as a variable element to induce asymmetric cell division, facilitating developmental diversity among species.
    1. Developmental Biology
    2. Neuroscience

    Lineage-specific intersection of endothelin and GDNF signaling in enteric nervous system development

    Denise M Poltavski, Alexander T Cunha ... Takako Makita
    Neural crest and placode lineages both contribute to the enteric nervous system, divergently utilizing Edn3-Ednrb and GDNF-Ret signaling.
    1. Developmental Biology

    Distinct functions of three Wnt proteins control mirror-symmetric organogenesis in the C. elegans gonad

    Shuhei So, Masayo Asakawa, Hitoshi Sawa
    The mirror-symmetric structure of the Caenorhabditis elegans gonad is established through the Wnt-independent function of a Frizzled protein and three Wnt proteins with distinct roles.
    1. Microbiology and Infectious Disease

    A system for functional studies of the major virulence factor of malaria parasites

    Jakob Cronshagen, Johannes Allweier ... Tobias Spielmann
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Cell Biology

    Rho-ROCK liberates sequestered claudin for rapid de novo tight junction formation

    Yuma Cho, Akari Taniguchi ... Junichi Ikenouchi
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cancer Biology
    2. Genetics and Genomics

    Single-cell multiomics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response

    Rebecca Warfvinge, Linda Geironson Ulfsson ... Göran Karlsson
    Single-cell analysis of CML patients bone marrow at diagnosis reveals coexistence of CD26-CD35+ healthy stem cells and CD26+CD35- CML stem cells, and how the ratio between these impacts TKI response.
    1. Cell Biology

    Centrosome Migration and Apical Membrane Formation in Polarized Epithelial Cells: Insights from the MDCK Cyst Model

    Po-Kai Wang, Keng-Hui Lin, Tang K Tang
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Human DDX6 regulates translation and decay of inefficiently translated mRNAs

    Ramona Weber, Chung-Te Chang
    DDX6 triggers inefficiently translated mRNA decay by interacting with the ribosome through its FDF motif via the 5'-3' mRNA decay pathway.

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