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    1. Ecology

    Diversity and asynchrony in soil microbial communities stabilizes ecosystem functioning

    Cameron Wagg, Yann Hautier ... Marcel GA van der Heijden
    Soil microbial diversity loss destabilizes the ability of the soil to function because greater diversity is needed to maintain temporal and functional asynchrony among different microbes.
    1. Developmental Biology

    Single-cell profiling coupled with lineage analysis reveals vagal and sacral neural crest contributions to the developing enteric nervous system

    Jessica Jacobs-Li, Weiyi Tang ... Marianne E Bronner
    Single-cell transcriptome analysis of sacral compared with vagal neural crest-derived cells in the developing chick enteric nervous system reveals both similarities and differences between these two cell populations.
    1. Microbiology and Infectious Disease

    Genetic code expansion enables visualization of Salmonella type three secretion system components and secreted effectors

    Moirangthem Kiran Singh, Parisa Zangoui ... Linda J Kenney
    Genetic code expansion (GCE) enables site-specific labeling and visualization of Salmonella secreted effectors, secretion system components and provides a viable alternative for labeling proteins that do not tolerate N- or C-terminal tags.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Small molecule-mediated refolding and activation of myosin motor function

    Michael B Radke, Manuel H Taft ... Dietmar J Manstein
    The small molecule EMD 57033 is one of a new class of pharmacological chaperones that stabilize, enhance the activity of, and correct stress-induced misfolding of myosin proteins.
    1. Neuroscience

    Taste sensing and sugar detection mechanisms in Drosophila larval primary taste center

    G Larisa Maier, Nikita Komarov ... Simon G Sprecher
    Drosophila larvae show taste multimodality and combinatorial sensing at gustatory organ level but also systemically as they employ complementary external and internal taste in sugar detection.
    1. Neuroscience

    A single pair of pharyngeal neurons functions as a commander to reject high salt in Drosophila melanogaster

    Jiun Sang, Subash Dhakal ... Youngseok Lee
    Fruit flies have special neurons in their pharynx with ionotropic receptors to prevent consuming too much salt, which was confirmed using a variety of behavioral and physiological assays.
    1. Cancer Biology

    Reduced mitochondrial transcription sensitizes acute myeloid leukemia cells to BCL-2 inhibition

    Laleh S. Arabanian, Jenni Adamsson ... Claes M. Gustafsson
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Plant Biology

    A novel bivalent chromatin associates with rapid induction of camalexin biosynthesis genes in response to a pathogen signal in Arabidopsis

    Kangmei Zhao, Deze Kong ... Seung Yon Rhee
    A previously uncharacterized type of bivalent chromatin plays an important role controlling the timely induction of genes involved in making a potent defense metabolite upon a pathogen signal in Arabidopsis.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Peptidoglycan precursor synthesis along the sidewall of pole-growing mycobacteria

    Alam García-Heredia, Amol Arunrao Pohane ... M Sloan Siegrist
    Peptidoglycan precursor synthesis occurs in both growing and non-growing regions of the mycobacterial cell surface.
    1. Neuroscience

    MagC, magnetic collection of ultrathin sections for volumetric correlative light and electron microscopy

    Thomas Templier
    The augmentation of resin-embedded sample blocks with magnetic resin allows remote actuation of ultrathin sections and deposition at high packing density onto silicon wafers for correlative light and electron microscopy.