The study of embryo-endometrial interactions in assembloid co-cultures identifies novel mechanisms of reproductive failure.

Improved characterisation of human embryonic lung development highlights human-mouse differences and facilitates the development of defined culture conditions for the expansion of self-renewing, multipotent human lung epithelial progenitor cells.

Gene editing to generate precisely matched primary human T cell populations demonstrates that the common autoimmune risk allele in the tyrosine phosphatase, PTPN22, promotes signaling in cells expressing a low-avidity, self-reactive TCR specific for a diabetes-associated self-antigen.

An integrative model of coordinated crawling in fruit fly maggots links neuromuscular dynamics to body-substrate mechanics in the presence of proprioceptive feedback.

Household transmission modeling qualified variation of individual infectiousness among infected persons, which could be caused by both biological factors and host behaviors.

Visual crowding from clutter outside the limits of binocular fusion can still have a significant impact on object recognition and visual perception in the peripheral field.

To facilitate human developmental biology research, CRISPR-mediated homologous recombination, tightly inducible gene knockdowns (CRISPRi) and overexpression (CRISPRa) have been efficiently applied to human organoids.

Habituation to mechanical vibration of crawling Drosophila larvae exhibits distinct time constants that characterize desensitization, re-sensitization, and further adaptation to repeated stimulus patterns.

The immune sensor RIG-I uses ATP-mediated compaction as a signaling trigger and a proofreading mechanism.

In mitotically aging yeast cells, the cytosol acidifies, the distances between the organellar membranes decrease dramatically, but crowding on the scale of the average size protein is relatively stable.