A computational study quantifies how macroscopic grid-like representations may emerge in the human brain using different hypotheses and navigation patterns, indicating the need to further characterize properties of grid cells.

Multicellular and socially aggregating prokaryotes contain previously undescribed, chaperone-based systems predicted to mediate defensive biological conflicts, several components of which are thematically similar antecedents of eukaryotic apoptosis pathways.

Expression pattern analysis of neurotransmitter synthesis, secretion, and reuptake machinery reveals animal-wide usage of neurotransmitters in both sexes of Caenorhabditis elegans.

Allosteric gating in a transient receptor potential channel is modulated by external sodium ions and a tarantula toxin.

Proteins locked into the immature HIV lattice can exploit its incomplete structure to form the essential protease dimer needed for viral maturation.

Genetic modulation in patterns of tissue conflict play a major role in the development and evolution of shape diversity.

The calcium-binding proteins synaptotagmin 7 and Doc2α act sequentially during asynchronous neurotransmitter release.

The METHYL-CpG-BINDING DOMAIN 7 (MBD7) complex promotes the activation (rather than repression) of transgenes that undergo DNA methylation and it does so without significantly altering their methylation status, placing this complex downstream of DNA methylation.

PRDM9 is widely conserved across vertebrates yet has been lost numerous times, as has its role in directing meiotic recombination.

Multiple RNA-seq approaches globally mapped RNA 3´ ends resulting in the discovery of numerous and diverse RNA regulators.