5,894 results found
    1. Cell Biology
    2. Developmental Biology

    A Non-stop identity complex (NIC) supervises enterocyte identity and protects from premature aging

    Neta Erez et al.
    A nuclear Non-stop identity complex (NIC) supervises enterocyte (EC) identity, preserves tissue homeostasis, and prevents premature aging by maintaining EC-specific gene expression, silencing non-relevant programs, and safeguarding large-scale nuclear organization.
    1. Neuroscience

    Brain endothelial cell TRPA1 channels initiate neurovascular coupling

    Pratish Thakore et al.
    Activation of TRPA1 channels on cerebral capillary endothelial cells initiates a retrograde signal that propagates and dilates upstream arterioles.
    1. Developmental Biology

    Deficient spermiogenesis in mice lacking Rlim

    Feng Wang et al.
    Genetic analyses in mice identifies Rlim in the spermatogenic cell lineage as a regulator of cytoplasmic reduction during spermiogenesis.
    1. Developmental Biology

    Retrograde ERK activation waves drive base-to-apex multicellular flow in murine cochlear duct morphogenesis

    Mamoru Ishii et al.
    Live-cell imaging and mathematical modeling reveal the physical basis of collective cell migration underlying spiral cochlear duct formation during murine inner ear development.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Emergence and diversification of a highly invasive chestnut pathogen lineage across southeastern Europe

    Lea Stauber et al.
    The chestnut blight fungus has successfully established an intermediary, diverse European bridgehead population, giving rise to a highly invasive clonal lineage spreading across southeastern Europe.
    1. Neuroscience

    Parabrachial opioidergic projections to preoptic hypothalamus mediate behavioral and physiological thermal defenses

    Aaron J Norris et al.
    Warm-activated parabrachial neurons contain overlapping dynorphin and enkephalin expressing subpopulations, project to preoptic hypothalamus, and mediate behavioral and physiological thermal defenses behaviors.
    1. Cell Biology

    One-shot analysis of translated mammalian lncRNAs with AHARIBO

    Luca Minati et al.
    Detection of translated lncRNAs through selective isolation of active ribosomes, ribosome-associated RNAs and corresponding de novo synthesised peptides.
    1. Developmental Biology
    2. Evolutionary Biology

    Developmental hourglass and heterochronic shifts in fin and limb development

    Koh Onimaru et al.
    Omics approaches reveal conserved and diversified gene regulation between fin and limb development.
    1. Developmental Biology
    2. Genetics and Genomics

    Precise base editing for the in vivo study of developmental signaling and human pathologies in zebrafish

    Marion Rosello et al.
    Base editors, with improved specificity and expanded PAM sequence recognition, can be used in zebrafish for the rapid and efficient introduction of single base pair mutations.
    1. Neuroscience

    Drosophila uses a tripod gait across all walking speeds, and the geometry of the tripod is important for speed control

    Chanwoo Chun et al.
    Drosophila uses a gait close to the tripod throughout its speed range, and changes in speed are accompanied by changes in the geometry of the tripod.

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