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By harnessing antibody fragments conjugated to small gold nanoparticles together with high pressure freezing, FIB/SEM milling and cryo-electron tomography, AMPA receptors were identified from mouse brain tissue.

First high-resolution structure of HGSNAT-acetyl-CoA complex, that describes the architecture of a novel transmembrane N-acetyltransferase fold and provides a molecular basis for MPS IIIC causing mutation induced destabilization of HGSNAT.

Enriching amphibian, Xenopus laevis, cutaneous mast cells confers protection against Batrachochytrium dendrobatidis chytrid fungus infections.

DNA gyrase, a regulator of bacterial genomes topology, is shown to undergo rearrangements while functioning on DNA in vitro, with important potential consequences for gyrase-targeted antibiotics activity and bacterial evolution.

Transient and weak interactions between the substrate-binding proteins of the ATP-binding cassette transporter OpuA can influence the transport efficiency.

Conformation-specific nanobodies enable to capture and solve the first GTP-bound active structure of a bacterial homolog of the Parkinson-associated LRRK2 protein, providing insights into the activation mechanism of these proteins.

Structural comparison and electrophysiology of OSCA channels shed light on potential structural features influencing response to poke stimulus.

A combination of molecular dynamics simulations and electron cryomicroscopy characterizes interactions of a pentameric ligand-gated ion channel with 25 lipid molecules, specifically in a functional state in which they were not previously observed.