3,198 results found
    1. Cell Biology

    ESCRT-III drives the final stages of CUPS maturation for unconventional protein secretion

    Amy J Curwin et al.
    The release of Acb1 protein from yeast cells requires the ESCRT-III complex to stabilize the compartment for unconventional protein secretion (CUPS).
    1. Cell Biology

    TRAIN (Transcription of Repeats Activates INterferon) in response to chromatin destabilization induced by small molecules in mammalian cells

    Katerina Leonova et al.
    Type I interferon signaling protects cells from the loss of epigenetic integrity, since it is activated in cells in response to accumulation of transcripts originating from normally silenced heterochromatin, caused by small-molecule-mediated nucleosome unfolding.
  1. Innovation Sprint 2019

    Innovation Sprint 2019: Project roundup

    From web tools to drive forward research discovery, citation and evaluation, to literature curation and knowledge extraction, we showcase the projects developed at this year’s Innovation Sprint.
  2. ReFigure logo

    ReFigure – connecting scientific insights across the web

    Introducing ReFigure, an open-source browser extension for linking, curating and sharing scientific insights across publishers.
    1. Evolutionary Biology
    2. Physics of Living Systems

    Morphogenesis: Mathematical models with frills

    Pierre A Haas
    The spectacular frill around the neck of the lizard Chlamydosaurus has its origins in a mechanical instability that arises during development.
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    1. Computational and Systems Biology

    Meta-Research: Incidences of problematic cell lines are lower in papers that use RRIDs to identify cell lines

    Zeljana Babic et al.
    The use of Research Resource Identifiers (RRIDs) improves the proper use of cell lines in the biomedical literature.
    1. Microbiology and Infectious Disease

    Research: A comprehensive and quantitative exploration of thousands of viral genomes

    Gita Mahmoudabadi, Rob Phillips
    A compendium of critical genomic numbers for viruses through the lenses of different viral classification systems.
  3. Living Science: Triaging Shakespeare

    Indira M Raman
    What if every creative endeavor had to go through Peer Review? Indira M Rama considers the possibility.
  4. Meta-Research: Tracking the popularity and outcomes of all bioRxiv preprints

    Richard J Abdill, Ran Blekhman
    Data are reported for the monthly number of uploads to and downloads from bioRxiv, and for the number of preprints that are later published in peer-reviewed journals.
  5. Point of View: Faculty appointments and the record of scholarship

    Amy Brand
    Academic review committees would benefit from more details about the contributions made by individual researchers to papers with multiple authors, and also from more information about other types of scholarly communication.

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