6,962 results found
    1. Evolutionary Biology
    2. Genetics and Genomics

    Circular RNA repertoires are associated with evolutionarily young transposable elements

    Franziska Gruhl et al.
    Evolutionary analyses suggest that most mammalian circRNAs did not emerge from common ancestral circRNA precursors, arguing against widespread functional conservation.
    1. Microbiology and Infectious Disease
    Mosquito infection by gametocytes from cultures exposed to dihydroartemisinin (DHA) from Figure 2, Portugaliza et al.

    Malaria: A Collection of Articles

    Edited by Olivier Silvie et al.
    eLife has recently published a wide range of papers on malaria, covering a diversity of themes including parasite biology, epidemiology, immunology, drugs and vaccines.
    1. Cell Biology
    2. Neuroscience

    TRPM7 is critical for short-term synaptic depression by regulating synaptic vesicle endocytosis

    Zhong-Jiao Jiang et al.
    Electrophysiological and live-cell imaging analyses identify a presynaptic function of Ca2+ influx via transient receptor potential melastatin 7 (TRPM7) channels.
    1. Neuroscience

    Memory recall involves a transient break in excitatory-inhibitory balance

    Renée S Koolschijn et al.
    Hippocampal activity during memory recall predicts a transient increase in the ratio between neocortical glutamate and GABA, thereby allowing otherwise dormant memories to be released.
    1. Neuroscience

    An open-source, high-performance tool for automated sleep staging

    Raphael Vallat, Matthew P Walker
    A robust automatic sleep-staging algorithm offers a high level of accuracy matching that of typical human interscorer agreement.
    1. Neuroscience

    Skipping ahead: A circuit for representing the past, present, and future

    Jennifer C Robinson, Mark P Brandon
    A circuit between the hippocampus, nucleus reunions, and prefrontal cortex organizes information about the past, present, and future into alternating theta sequences.
    1. Biochemistry and Chemical Biology
    2. Ecology

    Fungi: Sex and self defense

    Milton T Drott
    The fungus Aspergillus nidulans produces secondary metabolites during sexual development to protect itself from predators.
    Insight
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    1. Microbiology and Infectious Disease

    Monocyte-derived transcriptome signature indicates antibody-dependent cellular phagocytosis as a potential mechanism of vaccine-induced protection against HIV-1

    Shida Shangguan et al.
    Using single-cell CITE-seq to implicate monocytes as the cellular origin of a protective HIV vaccine gene signature.
    1. Cell Biology
    2. Developmental Biology

    Human embryo polarization requires PLC signaling to mediate trophectoderm specification

    Meng Zhu et al.
    Functional analyses of in vitro fertilized, preimplanation human embryos reveal that the first lineage segregation depends on cell polarization signaling that is regulated by Phospholipase C (PLC) activity.

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