In this episode we hear about the cocktail party effect, the role of psuedogene RNA in the immune response, the genetic origins of a common form of blindness, the flu vaccine, and the origins of schistosomiasis.
LRRC8A is an essential component of a mechanoresponsive ion channel signaling complex that tunes skeletal muscle differentiation, muscle cell size, function and metabolic pathways to regulate adiposity and systemic glycemia.
mTOR signaling regulates the morphology of a human-enriched neural stem cell population and thus contributes to the radial architecture of the developing human cortex with implications for neurodevelopmental disease.
Maternal positional information in the fly embryo can be read rapidly in spite of the gene-expression bottleneck and general examples of regulatory architectures that combine speed and accuracy are provided.
The transcriptomic profiles of the constituent monotherapies of synergistic drug pairs tend to be correlated and result in novel gene expression in the combinations.
