123 results found
    1. Neuroscience

    Cerebellar Purkinje Cells Control Posture in Larval Zebrafish (Danio rerio)

    Franziska Auer, Katherine Nardone ... David Schoppik
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Immunology and Inflammation
    2. Medicine

    NK cell exhaustion in Wilson’s disease revealed by single-cell RNA sequencing predicts the prognosis of cholecystitis

    Yong Jin, Jiayu Xing ... Qingsheng Yu
    Metabolic abnormalities in hepatocytes cause the alteration of transcriptional profile and function of immune cells in the tissue microenvironment.
    1. Cancer Biology
    2. Immunology and Inflammation

    Tissue-resident natural killer cells support survival in pancreatic cancer through promotion of cDC1-CD8 T activity

    Simei Go, Constantinos Demetriou ... Eric O Neill
    Tissue-resident natural killer cells are important mediators of CD8 T responses in human cancers and these cells can be harnessed to increase immunity against pancreatic ductal adenocarcinoma.
    1. Cell Biology

    Small-molecule Activation of TFEB Alleviates Niemann-Pick Disease Type C via Promoting Lysosomal Exocytosis and Biogenesis

    Kaili Du, Hongyu Chen ... Dan Li
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Microbiology and Infectious Disease

    A Novel Rapid Host Cell Entry Pathway Determines Intracellular Fate of Staphylococcus aureus

    Marcel Rühling, Fabio Schmelz ... Martin J Fraunholz
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology

    Rho-ROCK liberates sequestered claudin for rapid de novo tight junction formation

    Yuma Cho, Akari Taniguchi ... Junichi Ikenouchi
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Tuberculosis susceptibility in genetically diverse mice reveals functional diversity of neutrophils

    Mariëtta M Ravesloot-Chávez, Erik Van Dis ... Sarah A Stanley
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Microbiology and Infectious Disease

    Mycolactone causes destructive Sec61-dependent loss of the endothelial glycocalyx and vessel basement membrane: a new indirect mechanism driving tissue necrosis in Mycobacterium ulcerans infection

    Louise Tzung-Harn Hsieh, Belinda S Hall ... Rachel E Simmonds
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    An altered cell-specific subcellular distribution of translesion synthesis DNA polymerase kappa (POLK) in aging neurons

    Mofida Abdelmageed, Premkumar Palanisamy ... Anirban Paul
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Cancer Biology

    A multi-gene predictive model for the radiation sensitivity of nasopharyngeal carcinoma based on machine learning

    Kailai Li, Junyi Liang ... Hui Meng
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
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