Serotonergic signaling regulates sleep homeostasis through 5HT2b receptor in a small subset of neurons in the dorsal fan-shaped body in drosophila.

Functional imaging and circuit mapping in the Drosophila brain identifies neuropils where sleep-promoting and arousal-promoting neuronal networks converge.

Optogenetic activation reveals a larger role for the fly brain 'sleep switch' neurons in controlling both waking and sleeping behavioral responsiveness, partly via a parallel channel involving innexin6 electrical synapses.

Consolidation of long-term courtship memory in Drosophila is mediated by a novel class of sleep promoting neurons that reactivates dopaminergic neurons engaged earlier in memory acquisition during post-learning sleep.

An analysis of the first complete synaptic resolution connectome of Drosophila's navigation circuit uncovers neural network motifs supporting broadly relevant sensorimotor computations.

Spatiotemporal manipulations of insomniac reveal that this gene regulates the birth and development of sleep-regulatory neurons, enabling their proper function in adulthood.

Different methods for inducing sleep in Drosophila flies may be promoting distinct sleep stages with different functions when brain activity and gene expression are compared.

The circadian clock gates sleep drive by modulating sleep homeostat neurons.

As in humans, Drosophila hearts are able to maintain contractile performance during healthy aging, but this maintenance is associated with an increased susceptibility to progressive dysrhythmias that can lead to fibrillatory arrest.