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    1. Biochemistry and Chemical Biology
    2. Developmental Biology

    Reduction of DNA Topoisomerase Top2 reprograms the epigenetic landscape and extends health and life span across species

    Man Zhu, Meng Ma ... Jing Yang
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    TRPV4 overactivation enhances cellular contractility and drives ocular hypertension in TGFβ2 overexpressing eyes

    Christopher N Rudzitis, Monika Lakk ... David Križaj
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Genetics and Genomics

    Mettl5 coordinates protein production and degradation of PERIOD to regulate sleep in Drosophila

    Xiaoyu Wu, Xingzhuo Yang ... Juan Du
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Medicine
    2. Neuroscience

    The effect of transcutaneous auricular vagus nerve stimulation on cardiovascular function in subarachnoid hemorrhage patients: A randomized trial

    Gansheng Tan, Anna L Huguenard ... Eric C Leuthardt
    Transcutaneous auricular vagus nerve stimulation is a safe neuromodulatory treatment for subarachnoid hemorrhage patients, with potential benefits for restoring autonomic balance.
    1. Neuroscience

    Multi-dimensional oscillatory activity of mouse GnRH neurons in vivo

    Su Young Han, Shel-Hwa Yeo ... Allan E Herbison
    The gonadotropin-releasing hormone (GnRH) neurons controlling fertility exhibit abrupt increases in activity to generate luteinizing hormone (LH) pulses and a sustained oscillatory pattern of activity to generate the LH surge.
    1. Neuroscience

    Sigh generation in preBötzinger Complex

    Yan Cui, Evgeny Bondarenko ... Jack L Feldman
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Neuroscience

    A neurotrophin functioning with a Toll regulates structural plasticity in a dopaminergic circuit

    Jun Sun, Francisca Rojo-Cortes ... Alicia Hidalgo
    A novel molecular mechanism linking a neurotrophin with a Toll-family and kinase-less Trk-like receptors provides a direct link from molecules to structural circuit plasticity and modification of behaviour.
    1. Neuroscience

    Circadian control of a sex-specific behaviour in Drosophila

    Sabrina Riva, M Fernanda Ceriani ... D Lorena Franco
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Stem Cells and Regenerative Medicine

    Rejuvenating aged osteoprogenitors for bone repair

    Joshua Reeves, Pierre Tournier ... Shukry J Habib
    Short-term interventions, including intermittent fasting, boosting cellular energy, and promoting beneficial gut bacteria, rejuvenate osteoprogenitors in aged animals and, when combined with localized Wnt, restore youthful bone healing.
    1. Cell Biology
    2. Developmental Biology

    Ciliary length regulation by intraflagellar transport in zebrafish

    Yi Sun, Zhe Chen ... Chengtian Zhao
    The speed of intraflagellar transport, influenced by particle size, shows a positive correlation with ciliary length in zebrafish.
    Version of Record
    Short Report
    • Valuable
    • Solid
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