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    1. Neuroscience

    Hippocampal remapping induced by new behavior is mediated by spatial context

    Samuel J. Levy, Michael E. Hasselmo
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    Social observation enhances cross-environment activation of hippocampal place cell patterns

    Xiang Mou, Daoyun Ji
    Place cells associated with track-running are activated in rats staying in a nearby box while another rat running on the track, suggesting that social observation facilitates spatial memory representations.
    1. Neuroscience

    Learning-related contraction of gray matter in rodent sensorimotor cortex is associated with adaptive myelination

    Tomas Mediavilla, Özgün Özalay ... Daniel J Marcellino
    Learning produces dynamic white matter volumetric changes in the rodent brain observed by voxel-based morphometry on longitudinal structural MRI for which estimated white matter volume reflects adaptive myelination in the cortex.
    1. Neuroscience

    Surface color and predictability determine contextual modulation of V1 firing and gamma oscillations

    Alina Peter, Cem Uran ... Martin Vinck
    Colored surfaces induce strong gamma-synchronization yet sparse firing in V1 when receptive field inputs are predicted from the surrounding spatial context.
    1. Computational and Systems Biology
    2. Neuroscience

    Real-time, low-latency closed-loop feedback using markerless posture tracking

    Gary A Kane, Gonçalo Lopes ... Mackenzie W Mathis
    DeepLabCut-Live allows for real-time, ultra-low latency posture tracking of animals.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Increased longevity due to sexual activity in mole-rats is associated with transcriptional changes in the HPA stress axis

    Arne Sahm, Matthias Platzer ... Philip Dammann
    The fact that sexual activity/reproduction doubles the lifespan of certain rodent species is most likely linked to critical changes in the regulation of the hypothalamic–pituitary–adrenal stress axis.
    1. Cell Biology
    2. Medicine

    Chinese natural compound decreases pacemaking of rabbit cardiac sinoatrial cells by targeting second messenger regulation of f-channels

    Chiara Piantoni, Manuel Paina ... Mirko Baruscotti
    A Traditional Chinese Medicine botanical drug exerts a competitive antagonism on the cAMP-induced modulation of sinoatrial node pacemaker channels and this functional inhibition reduces the slope of the diastolic depolarization hence spontaneous cell automaticity.
    1. Computational and Systems Biology
    2. Chromosomes and Gene Expression

    NF-κB oscillations translate into functionally related patterns of gene expression

    Samuel Zambrano, Ilario De Toma ... Alessandra Agresti
    NF-κB oscillations synchronize to external perturbations as a damped oscillator, producing different transcription dynamics.
    1. Developmental Biology

    Extensive and diverse patterns of cell death sculpt neural networks in insects

    Sinziana Pop, Chin-Lin Chen ... Darren W Williams
    Developmental cell death plays a key role during insect neurogenesis and is increased in specific neuronal populations in flies that have evolved flightlessness.
    1. Structural Biology and Molecular Biophysics

    Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival

    Vladimir Chubanov, Silvia Ferioli ... Thomas Gudermann
    Mice deficient in the TRPM6 channel suffer from impaired prenatal development, shortened lifespan, growth deficit and disturbed energy balance due to a defect in epithelial Mg2+ uptake, thus highlighting a pivotal role of TRPM6 in organismal Mg2+ homeostasis.