5,127 results found
    1. Neuroscience

    Demixed principal component analysis of neural population data

    Dmitry Kobak et al.
    A new data analysis tool provides a concise way of visualizing neural data that summarizes all the relevant features of the population response in a single figure.
    1. Human Biology and Medicine

    Reverse translation of adverse event reports paves the way for de-risking preclinical off-targets

    Mateusz Maciejewski et al.
    Careful analysis of adverse drug reaction reports reveals noise and biases embedded in this data and allows for systematic mitigation of these effects to produce much more robust understanding of side effects of marketed drugs.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    A phylogenetic transform enhances analysis of compositional microbiota data

    Justin D Silverman et al.
    The PhILR transform uses an evolutionary model to overcome statistical challenges associated with microbiota surveys.
    1. Human Biology and Medicine

    Adverse Drug Reactions: The benefits of data mining

    Audrey Bone, Keith Houck
    Careful analysis of a database populated by physicians and patients sheds new light on the side effects of drugs.
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  1. Research: Gender bias in scholarly peer review

    Markus Helmer et al.
    Gender-bias in peer reviewing might persist even when gender-equity is reached because both male and female editors operate with a same-gender preference whose characteristics differ by editor-gender.
  2. Research: The readability of scientific texts is decreasing over time

    Pontus Plavén-Sigray et al.
    Scientific abstracts have become less readable over the past 130 years, in part because recent texts include more general scientific jargon than older texts.
  3. Tutorial: How to draw the line in biomedical research

    Lisa Huang et al.
    When analysing the data in a two-dimensional scatter plot, researchers should consider plotting the three regression lines that can be calculated for such a plot.
    1. Epidemiology and Global Health
    2. Human Biology and Medicine

    Standardized mean differences cause funnel plot distortion in publication bias assessments

    Peter-Paul Zwetsloot et al.
    Funnel plots of the Standardized Mean Difference versus the standard error are prone to distortion, leading to false-positive tests for funnel plot asymmetry, and therefore using the Normalised Mean Difference, or a sample size-based precision estimate, are more reliable alternatives.
    1. Human Biology and Medicine

    Science Forum: An open investigation of the reproducibility of cancer biology research

    Timothy M Errington et al.
    The Reproducibility Project: Cancer Biology will generate a high-quality dataset to explore questions about the reproducibility of research, and will make all data, analysis and other research materials openly available to the research community.
  4. Living Science: In numbers we trust?

    Eve Marder
    Scientists go to great lengths to ensure that data are collected and analysed properly, so why do they apply different standards to data about the number of times research papers have been cited and viewed?

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