A female specifically expressed new protein-coding gene that has emerged out of non-coding sequences without detectable signatures of adaptive evolution affects female pregnancy cycles.

Deep sequencing of transcriptomes from closely related taxa shows that the whole genome can become subject to evolutionary testing within a short time frame via de novo evolution of genes.

Single-cell RNA-sequencing and germline substitutions provide novel insights into how testis is a hotspot for evolutionary innovation of genes, expression, and mutation at the single-cell level.

A lexicon to help scientists and philosophers discuss the meaning of function in molecular biology more clearly is proposed.

The first genomic view of beetle luciferase evolution indicates evolutionary independence of luciferase between fireflies and click-beetles, and provide valuable datasets which will accelerate the discovery of new biotechnological tools.

Simultaneous targeting of loci by pathways that promote euchromatin and heterochromatin primes transcribed genes for epimutations in the form of CG DNA methylation.

Mutagenizing sequences enriched with promoter motifs creates gene expression de novo, and helps to understand promoter logic, regulatory evolution, and the birth of de novo genes.

Homology information implicit in regions of conserved synteny allows quantification of gene origination by complete sequence divergence, revealing a larger-than-expected role for other mechanisms of origin, including de novo origination.

DNA methylation deposition is dependent on the presence of H3K4me3 and H3K36me3 histone marks.

The analysis of mass-spectrometry data for all possible open reading frames reveals protein evidence for evolutionarily young, unannotated proteins with distinct characters.