A series of quantitative behavioural and opto-physiological analyses using a novel robot microscope system reveals that C. elegans computes the time-differential and time-integral of sensory information for decision-making during olfactory navigation.

Older adults show reduced adaptation of decision-making strategies to dynamically changing situational demands.

Ketamine, an NMDA receptor antagonist and experimental model for schizophrenia, produces decision-making deficits in monkeys, which are predicted by a lowering of cortical excitation-inhibition balance in a spiking circuit model.

Speeded value-based decisions between two options can be affected by a third, high-value distractor that captures attention and slows down the choice process.

Dopamine attenuates exploration during decision-making via a reduction of neural tracking of uncertainty.

Temporal uncertainty interferes with the timely onset of evidence accumulation in perceptual decision making prompting the brain to rely instead on statistical regularities in the temporal structure of the environment.

Intraoperative human brain recordings during a memory task reveal that when participants inhibit memory formation, the subthalamic nucleus shows higher beta power and beta coherence with areas of the lateral cortex implicated in memory processing.

The value of any choice is not static but dynamically changes as a function of the context of the alternatives even if they are seemingly irrelevant.

A new platform for imaging live Drosophila adults yields vivid movies of the midgut over prolonged time scales, opening the door to the real-time study of organ renewal dynamics in a near-native context.

Perceptual decision making, even in simple scenarios, is affected by sensory and decisional choice biases.