7,527 results found
    1. Developmental Biology
    2. Evolutionary Biology

    Evolutionary expansion of apical extracellular matrix is required for the elongation of cells in a novel structure

    Sarah Jacquelyn Smith et al.
    A new morphological structure evolved through extreme changes in cell height requires novel connections to an extracellular matrix network, which predates the origin of structure.
    1. Microbiology and Infectious Disease

    ODELAM, rapid sequence-independent detection of drug resistance in isolates of Mycobacterium tuberculosis

    Thurston Herricks et al.
    Time-lapse live cell imaging of single Mycobacterium tuberculosis bacilli growing into small colonies enables their rapid phenotypic characterization including anti-microbial resistance and heteroresistance in clinical isolates.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Translational control of one-carbon metabolism underpins ribosomal protein phenotypes in cell division and longevity

    Nairita Maitra et al.
    Extensive molecular profiling shows how loss of highly similar, paralogous ribosomal proteins lead to distinct phenotypic outputs, through translational control of specific mRNAs.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Retrocopying expands the functional repertoire of APOBEC3 antiviral proteins in primates

    Lei Yang et al.
    Genomes take advantage of the gene-duplicating ability of retroelements to birth novel innate immune defense genes.
    1. Cell Biology
    2. Developmental Biology

    Maternal spindle transfer overcomes embryo developmental arrest caused by ooplasmic defects in mice

    Nuno Costa-Borges et al.
    Maternal spindle transfer is a feasible approach to enhance embryonic developmental of compromised oocytes, which can represent a new strategy for patients with forms of infertility refractory to current treatments.
    1. Neuroscience

    MeCP2 in cholinergic interneurons of nucleus accumbens regulates fear learning

    Ying Zhang et al.
    Robust fear learning deficits and decreased tonic activity of NAc cholinergic interneurons caused by depletion of MeCP2 could be attributed to an elevation in α2-containing GABAA receptors.
    1. Structural Biology and Molecular Biophysics

    ER-luminal [Ca2+] regulation of InsP3 receptor gating mediated by an ER-luminal peripheral Ca2+-binding protein

    Horia Vais et al.
    Calcium release from the endoplasmic reticulum through the IP3 receptor ion channel is strongly regulated by a calcium-binding protein in the lumen of the endoplasmic reticulum.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    A new protocol for single-cell RNA-seq reveals stochastic gene expression during lag phase in budding yeast

    Abbas Jariani et al.
    A new high-throughput method for single-cell RNA-seq in yeast cells shows how stochastic expression of glucose-repressed genes contributes to cell-to-cell differences during adaptation to an environmental change.

Refine your results by:

Type
Research categories