644 results found
    1. Neuroscience

    Intermittent subthalamic nucleus deep brain stimulation induces risk-aversive behavior in human subjects

    Shaun R Patel et al.
    Deep brain stimulation can selectively modify neural activity within the subthalamic nucleus to modify decisions under uncertainty in human subjects.
    1. Neuroscience

    Forniceal deep brain stimulation induces gene expression and splicing changes that promote neurogenesis and plasticity

    Amy E Pohodich et al.
    Forniceal deep brain stimulation is a promising treatment for several neuropsychiatric disorders as it upregulates synaptic and neurogenesis-associated genes, normalizes genes misregulated in Rett syndrome mice, and regulates genes altered in intellectual disability and major depression.
    1. Neuroscience

    Magnetothermal genetic deep brain stimulation of motor behaviors in awake, freely moving mice

    Rahul Munshi et al.
    Magnetothermal neuromodulation providing quick, tetherless, precise on and off switching of neurons deep in the brain of freely moving animals is orthogonal to optogenetics and a breakthrough in remote modulation techniques.
    1. Neuroscience

    Human subthalamic nucleus activity during non-motor decision making

    Baltazar A Zavala et al.
    Intraoperative human brain recordings during a memory task reveal that when participants inhibit memory formation, the subthalamic nucleus shows higher beta power and beta coherence with areas of the lateral cortex implicated in memory processing.
    1. Neuroscience

    Ventromedial prefrontal cortex stimulation enhances memory and hippocampal neurogenesis in the middle-aged rats

    Albert Liu et al.
    High-frequency stimulation of the ventromedial prefrontal cortex, which enhances memory and hippocampal neurogenesis, is a novel target for treatment of dementia-related diseases.
    1. Human Biology and Medicine
    2. Neuroscience

    Theta-burst microstimulation in the human entorhinal area improves memory specificity

    Ali S Titiz et al.
    Precisely targeted, low current brain microstimulation is sufficient to enhance human memory.
    1. Human Biology and Medicine
    2. Neuroscience

    Dopamine-dependent scaling of subthalamic gamma bursts with movement velocity in patients with Parkinson’s disease

    Roxanne Lofredi et al.
    Bradykinesia in Parkinson's disease may be associated to a dopamine-dependent recruitment failure of subthalamic activity in short bursts of gamma synchrony.
    1. Developmental Biology

    Addressing the ethical issues raised by synthetic human entities with embryo-like features

    John Aach et al.
    Guidelines governing research into embryos need to be updated in a way that reflects the moral status of synthetic human entities generated using the methods of synthetic biology.

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