The default mode network in the brain is activated during the performance of executive-type tasks when a substantial change in cognitive contents is required.

In the human brain, default mode network BOLD deactivations can be accompanied by both increases and decreases in glucose metabolism, depending on the respective metabolic demands of task-positive cognitive control and attention networks.

Unprecedented 4D spatiotemporal infant regional cerebral blood flow framework and region-specific physiology–function coupling across infancy were elucidated, highlighting strong physiology–function coupling specifically at the default-mode network to meet extraneuronal metabolic demand for network emergence.

Prior experience alters content-specific neural representations of visual input in frontoparietal and default-mode networks.

Functional hypoconnectivity between ‘social brain’ default mode circuitry and visual association cortex underpins a subtype of autistic toddlers with a strong preference to attend to the non-social visual world.

Functional neuroimaging in the human brain reveals the neurocognitive mechanisms that underpin the experience of mind-wandering during reading, explaining why comprehension is impaired.

Human intracranial electroencephalography recordings across 177 participants and four diverse episodic memory experiments demonstrate how the anterior insula node of the salience network orchestrates dynamics of large-scale brain networks.

Default mode network and visual cortex are connected via two parallel pathways that differentially respond to the processing of visual scenes and semantic information about objects, reflecting domain-specific organisation.

Changes in the interpretation of specific scenes in a narrative trigger corresponding updates in the neural patterns evoked by those scenes in the default mode network.

People’s neural activity travels between a small number of brain states based on what they are thinking and paying attention to.