The default mode network in the brain is activated during the performance of executive-type tasks when a substantial change in cognitive contents is required.

Prior experience alters content-specific neural representations of visual input in frontoparietal and default-mode networks.

Functional hypoconnectivity between ‘social brain’ default mode circuitry and visual association cortex underpins a subtype of autistic toddlers with a strong preference to attend to the non-social visual world.

When subjects perform spatial judgments in environments of increasing scale, brain activity shifts along posterior-anterior gradients, advancing from the visual system to the default-mode network.

Patterns of communication between the thalamus and the cortex are correlated with anesthesia-induced loss of consciousness and recovery.

Cerebellar functional regions follow a gradual organization, which progresses from primary (motor) to transmodal (Default Mode Network) regions, and a secondary axis extends from task-unfocused to task-focused processing.

Striatal dopamine 2/3 receptor (D2/3R) availability is related to working memory-induced functional connectivity changes in the default mode network, and this mediates the relationship between D2/3Rs and task performance.

The amyloid patterns overlap with the default-mode network, whereas the tau patterns overlap with distinct functional networks and are associated with a loss of anatomical connectivity and multiple cognitive functions.

An fMRI experiment reveals distinct brain regions that respond in a graded manner as humans process distance information across increasing spatial scales.