Size threshold and suprastructure formation are key parameters that control the infective potential of amyloid fibrils as prion particles.

Single-cell mRNA sequencing shows that the impact of infection with influenza virus varies dramatically from one cell to another.

The packaging signal in HIV-1 genomic RNA supports in vitro particle assembly more efficiently than control RNAs, probably explaining its selective packaging during virus assembly in vivo.

A survey of researchers at the Montreal Neurological Institute and Hospital provides insights into the challenges and opportunities involved in adopting an open science policy across an entire patient-oriented academic institution.