5,323 results found
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    The physical dimensions of amyloid aggregates control their infective potential as prion particles

    Ricardo Marchante et al.
    Size threshold and suprastructure formation are key parameters that control the infective potential of amyloid fibrils as prion particles.
    1. Microbiology and Infectious Disease

    Extreme heterogeneity of influenza virus infection in single cells

    Alistair B Russell et al.
    Single-cell mRNA sequencing shows that the impact of infection with influenza virus varies dramatically from one cell to another.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Efficient support of virus-like particle assembly by the HIV-1 packaging signal

    Mauricio Comas-Garcia et al.
    The packaging signal in HIV-1 genomic RNA supports in vitro particle assembly more efficiently than control RNAs, probably explaining its selective packaging during virus assembly in vivo.
    1. Developmental Biology
    2. Human Biology and Medicine

    Correction: HIF-2α is essential for carotid body development and function

    David Macias et al.
    1. Evolutionary Biology

    Correction: More effective drugs lead to harder selective sweeps in the evolution of drug resistance in HIV-1

    Alison F Feder et al.
    1. Cancer Biology
    2. Human Biology and Medicine

    Correction: The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer

    James D Joseph et al.
    1. Human Biology and Medicine

    Correction: A distinct p53 target gene set predicts for response to the selective p53-HDM2 inhibitor NVP-CGM097

    Sébastien Jeay et al.
    1. Neuroscience

    Correction: Affective bias as a rational response to the statistics of rewards and punishments

    Erdem Pulcu, Michael Browning

  9. Correction: Replication Study: Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

    Xiaochuan Shan et al.
    1. Computational and Systems Biology

    Meta-Research: Centralized scientific communities are less likely to generate replicable results

    Valentin Danchev et al.
    Analysis of data on drug-gene interactions suggests that decentralized collaboration will increase the robustness of scientific findings in biomedical research.
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