9,847 results found
    1. Evolutionary Biology
    2. Stem Cells and Regenerative Medicine

    A conserved strategy for inducing appendage regeneration in moon jellyfish, Drosophila, and mice

    Michael J Abrams, Fayth Hui Tan ... Lea Goentoro
    Amino acid and sugar supplement induce appendage/limb regeneration in cnidarians, insects, and mammals.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Mettl3-mediated m6A modification of Fgf16 restricts cardiomyocyte proliferation during heart regeneration

    Fu-Qing Jiang, Kun Liu ... Xu-Feng Qi
    Mettl3 post-transcriptionally reduces Fgf16 mRNA levels through an m6A-Ythdf2-dependen pathway, thereby controlling cardiomyocyte proliferation and heart regeneration.
    1. Developmental Biology

    Cardiac neural crest contributes to cardiomyocytes in amniotes and heart regeneration in zebrafish

    Weiyi Tang, Megan L Martik ... Marianne E Bronner
    Lineage analysis reveals that cardiac neural crest contributes to cardiomyocytes across vertebrates and consistent with this, the neural crest gene regulatory program is reactivated upon heart regeneration in zebrafish.
    1. Stem Cells and Regenerative Medicine
    2. Neuroscience

    A functional genomics screen in planarians reveals regulators of whole-brain regeneration

    Rachel H Roberts-Galbraith, John L Brubacher, Phillip A Newmark
    A gene expression-guided functional screen identifies factors and cell types that regulate diverse aspects of neural regeneration in planarians.
    1. Stem Cells and Regenerative Medicine

    Selective amputation of the pharynx identifies a FoxA-dependent regeneration program in planaria

    Carolyn E Adler, Chris W Seidel ... Alejandro Sánchez Alvarado
    A chemical method has been developed for studying single organ regeneration and fate specification of stem cells in an adult organism.
    1. Cell Biology
    2. Neuroscience

    Structural plasticity of actin-spectrin membrane skeleton and functional role of actin and spectrin in axon degeneration

    Guiping Wang, David J Simon ... Xiaowei Zhuang
    Neurotrophin deprivation leads to rapid caspase-independent disassembly of the actin-spectrin-based membrane skeleton and spectrin-dependent retrograde signaling in axon degeneration.
    1. Epidemiology and Global Health

    Inference of the SARS-CoV-2 generation time using UK household data

    William S Hart, Sam Abbott ... Robin N Thompson
    Updated estimates of the generation time of SARS-CoV-2 infections indicate that the generation time has become shorter.
    1. Developmental Biology
    2. Neuroscience

    Retinoic acid signaling mediates peripheral cone photoreceptor survival in a mouse model of retina degeneration

    Ryoji Amamoto, Grace K Wallick, Constance L Cepko
    Retinoic acid signaling from Muller glia is necessary for cone photoreceptor survival in the peripheral retina and is sufficient to promote cone survival in the central retina during retinal degeneration.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Pigment cell progenitor heterogeneity and reiteration of developmental signaling underlie melanocyte regeneration in zebrafish

    William Tyler Frantz, Sharanya Iyengar ... Craig J Ceol
    Zebrafish pigment cell progenitors are a heterogeneous class of adult tissue-resident cells which reiterate developmental signaling during melanocyte regeneration.
    1. Developmental Biology

    Renal interstitial cells promote nephron regeneration by secreting prostaglandin E2

    Xiaoliang Liu, Ting Yu ... Chi Liu
    During nephron regeneration, renal interstitial cells promote the proliferation of renal progenitor cells by secreting PGE2, thus forming the microenvironment of renal progenitor cells.

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