Transcriptomic analyses of Malabar grouper show pathways known to be involved in metamorphosis are also upregulated at an early stage of larval development, suggesting an additional function during early development.

Comparative transcriptome analyses of human placenta reveal regulatory divergence between native highlanders and lowland immigrants living at high altitude, and a sex-biased pattern of genetic adaptation.

Targeted manipulation of the locus coeruleus noradrenaline circuitry combined with extensive transcriptomic analyses in the mouse hippocampus reveal a unique set of noradrenaline-dependent, stress-related genes and point to astrocytic engagement.

PSTPIP2 reduced IL-19 secretion by inhibiting activation of the NF-κB pathway in renal tubular epithelial cells (RTECs), reducing the generation of neutrophil extracellular trap, which can participate in both aristolochic acid I-induced renal injury and apoptosis in RTECs.

Molecular analyses reveal the neuroendocrine control of seasonal life-history transitions in birds.

Analysis of the tumor microenvironment reveals that pancreatic tumors experience metabolic stress caused by immune cell degradation of the amino acid arginine, and that pancreatic cancers cope by synthesizing arginine to provide access this amino acid despite low tumor availability.

T3 is taken up by axonal termini and is retrogradely transported into endosomal vesicles to the cell nucleus, where it regulates gene expression.

T3 regulates BAT thermogenesis by controlling the expression of genes involved in the management of metabolic fuels as well as tissue plasticity.